Volumetric and viscometric studies of urea in binary aqueous solutions of glucose at different temperatures

Volumetric and viscometric studies of glucose in binary aqueous solutions of urea at different temperatures

“…The tendency of higher Dl # 2 values over the Dl # 1 values indicates that the stronger solute-solvent interaction is present within the glucose in aqueous binary urea solution. Whereas in our earlier study [10], the smaller Dl # 2 values over the Dl # 1 values established very weak solute-solvent interaction. Therefore, the situation is suggesting that the formation of the transition state is less favoured in the presence of glucose; rather the formation of transition state is accompanied by the rapture and distortion of the intermolecular bonds in solvent structure.…”

“…Thus the negative value of the difference of these two volumes ðU v À V m Þ, thereby shows the presence of strong solute-solvent interactions. While, in our earlier work [10] negative U v values were obtained possibly due to the weak solute-solvent or solute-solute interactions. Further the U v values decrease with increasing temperature almost in every mass% of urea solutions that may be attributed to the breaking of hydrogen bonding and subsequent destruction of the ice-like structure of the solvent water.…”

“…Relevant activation parameters were also calculated on the basis of transition state theory of relative viscosity of glucose in binary aqueous urea solutions. Obtained results have also been compared with our earlier studies of urea in binary aqueous glucose solutions [10].…”

“…Several workers have also recognized that some important knowledge about intermolecular interactions can be inferred from accurate volumetric and viscometric data [6][7][8][9]. In our laboratory, we have been pursuing volumetric and viscometric studies of urea in binary aqueous solutions of glucose at different temperatures for understanding the nature and thermodynamic behaviour of bio-fluids in the body-system [10]. Although the earlier studies on interactions in single, binary, and ternary aqueous solutions are quite extensive, yet the volumetric and viscometric studies of glucose in binary aqueous solutions of urea are limited in the literature.…”

Enthalpic pairwise self-interactions of urea and its four derivatives in (dimethylformamide + water) mixtures rich in water at T = 298.15 K

“…For instance, urea and its alkyl-substituted compounds are often considered as the breaker of water structure [6], the denaturants of native proteins [7] and have a good solubilizing effect on hydrocarbons and polar molecules [8,9]. In recent decades, many researchers have discussed the interactions of urea and its derivatives in aqueous solution conditions through thermodynamic and other properties [10][11][12][13][14][15][16][17]6], as well as by theoretical computation [18,19]. However, the mechanism of protein denaturation by urea and its homologues is still obscure and remains as an open problem [20][21][22][23], i.e.…”