Volumetric modulated arc therapy treatment planning assessment for low-risk prostate cancer in radiotherapy

Zulkafal, Hafiz Mubibbullah; Khan, Muhammad Ashraf; Ahmad, Muhammad Shakil; Akram, Muhammad; Buzdar, Saeed Ahmad; Iqbal, Khalid

doi:10.4103/ccij.ccij_38_17

Cited by 6 publications

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“…Table 1 shows values of two statistical tests: mean standard error and standard deviation for HI, UI, mDHI, coverage index and rDHI. The data are divided into three groups, and these are 1 st group (1-15), 2 nd group (16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30) and the 3 rd group (1-30). The values of mean standard error and standard deviation of the first set which was treated with 4500 cGy and the 2 nd set treated with 5000 cGy were compared.…”

Section: Resultsmentioning

confidence: 99%

“…We have used this technique as this methodology can improve the coverage of critical place tumour coverage and the dose to normal tissues can be reduced. We have calculated different indices: moderate dose homogeneity index (mDHI), radical dose homogeneity index (rDHI), coverage index, homogeneity and uniformity index (UI) according to defined relations 18 . These indices are used to study dose distribution verification for all these plans in our current study.…”

Section: Introductionmentioning

confidence: 99%

“…We have calculated different indices: moderate dose homogeneity index (mDHI), radical dose homogeneity index (rDHI), coverage index, homogeneity and uniformity index (UI) according to defined relations. 18 These indices are used to study dose distribution verification for all these plans in our current study. Statistical analysis software SPSS Statistics (IBM SPSS® Statistics 24.0) is utilised in descriptive statistics, charts, plots of distributions and trend generated tabulated reports and complex statistical analysis, so it is a comprehensive system for data analysis.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of three dimensional conformal radiation therapy of oesophageal cancer: a dosimetric study

et al. 2018

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AimsThe main objective of this research work is to compare the dosimertic effect on lower and upper oesophagus cancer treatment using 3D conformal radiotherapy as well as to evaluate the doses administered to the organs at risk.Materials and methodsIn this study, a cohort of 30 oesophageal cancer patients between the ages of 45 and 67 years registered during March 2017 to February 2018 was considered. These patients were treated through 3D conformal radiotherapy using four-field technique. Beam energy of 15 MV from Varian DHX linear accelerator was used. The given 30 patients were divided into two groups. The 1st group of 15 patients with upper oesophagus cancer was prescribed 5000 cGy doses, and the 2nd group of remaining 15 patients with lower oesophagus cancer was prescribed 4500 cGy. Computed tomography scans of every patient were obtained and then transmitted to Eclipse TPS for generating treatment plans. All radiotherapy plans were evaluated through various dosimetric indices. Statistical analysis software SPSS was utilised to get the values of means standard error and standard deviation of these indices for the treatment plan evaluation.ResultsUniformity index (UI) calculated for first group of patients showed difference of 7·4% from ideal value. A difference of 7% between ideal and calculated UI value was observed in 2nd group of patients. The values of other dosimetric indices like coverage, homogeneity, moderate dose homogeneity index (mDHI) and radical dose homogeneity index (rDHI) were found in limits specified by the Radiation Therapy and Oncology Group. The maximum difference of 6% was observed between the coverage mean values of 1stand 2ndgroup treatment plans.ConclusionFor oesophageal cancer, 3D conformal radiotherapy using four-field treatment plans shows homogeneous distribution of dose around the target and limits the dose to organ at risk.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Evaluation of three dimensional conformal radiation therapy of oesophageal cancer: a dosimetric study

et al. 2018

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“…2 The Varian version of VMAT is RapidArc, which was developed by Karl Otto in 2008, and it utilises dose painting techniques for increasing dose per fraction to the target site. [3][4][5] For the treatment of head and neck cancer, Mohan et al used simultaneous integrated boost (SIB) in IMRT that showed the advantages of shorter treatment time, improved conformity of target and reduced doses to Organs at Risk (OARs) as well as better dose hotspot control. 6 Jin et al utilised SIB in VMAT for nasopharyngeal cancer and proved that two-arcs SIB VMAT is better for target coverage with significantly shorter delivery times, but it showed no improvement for doses to the OAR.…”

Section: Introductionmentioning

confidence: 99%

RapidArc treatment planning quality assurance using electronic portal imaging device for cervical cancer

et al. 2019

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Purpose:The main objective of this study is to assure the quality of cervical cancer treatment plans using an electronic portal imaging device (EPID) in RapidArc techniques.Materials and Methods:Fifteen cases of cervical cancer patients undergoing RapidArc technique were selected to evaluate the quality assurance (QA) of their treatment. The computed tomography (CT) of each patient was obtained with 3-mm-slice thickness and transferred to the Eclipse treatment planning system. The prescribed dose (PD) of 50·4 Gy with 1·8 Gy per fraction to planning target volume (PTV) was used for each patient. The aim of treatment planning was to achieve 95% of PD to cover 97%, and dose to the PTV should not receive 105% of the PD. All RapidArc plans were created using the AAA algorithm and treated on Varian DHX using 6 MV photon beam, with two full arcs. Gamma analysis was used to evaluate the quality of the treatment plans with accepting criteria of 95% at 3%/3 mm.Results:In this study, maximum and average gamma values were 2·53 ± 0·409 and 0·195 ± 0·059 showing very small deviation and indicating the smaller difference between both predicted and portal doses. Gamma Area changes from > 0·8 to > 1·2. SD increased to 5·4% and mean standard error increased to 4·67%.Conclusion:On the basis of these outcomes, we can summarise that the EPID is a useful tool for QA in standardising and evaluating RapidArc treatment plans of cervical cancer in routine clinical practice.

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“…[5][6][7][8][9] VMAT is an arc-based IMRT having the capability of modulating gantry rotation speed in addition to variable dose rate and changing treatment aperture shapes. 10 It is the advanced form of IMRT that can deliver the whole treatment within a few arcs with a reduced treatment time. 11 Short treatment time has the benefit of improving patient comfort, reduced intra-fraction motion and enhances overall treatment outcomes.…”

Section: Introductionmentioning

confidence: 99%

Dose verification of volumetric-modulated arc therapy using one-dimensional and two-dimensional dosimeters

et al. 2018

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Purpose: To verify dose delivery and quality assurance of volumetric modulated arc therapy (VMAT) for head and neck cancer.Method: The Imaging and Radiation Oncology Core Houston (IROC-H) head and neck phantom with thermo-luminescent dosimeters (TLDs) and films, were imaged with computed tomography scan and the reconstructed image was transferred to pinnacle treatment planning system (TPS). On TPS the planning target volume (PTV), secondary target volume (STV) and organ at risk (OAR) were delineated manually and a treatment plan was made. The dose constraints were determined for the concerned organs according to IROC-H prescription. The treatment plan was optimized using adoptive convolution algorithm to improve dose homogeneity and conformity. The dose calculation was performed using C.C Convolution algorithm and a Varian True Beam linear accelerator was used to deliver the treatment plan to the head and neck phantom. The delivered radiation dose to the phantom was measured through TLDs and GafChromic EBT2 films. The dosimetric performance of the VMAT delivery was studied by analyzing percent dose difference, iso-dose line profile and gamma analysis of the TPS computed dose and linac delivered doses.Result: the percent dose difference of 3.8% was observed between the planned and measured doses of TLDs and a 1.5mm distance to agreement (DTA) was observed by comparing iso-dose line profiles. Passed the gamma criteria of 3%/3 mm was with good percentages. Conclusion:The dosimetric performance of VMAT delivery for a challenging head and neck radiotherapy can be verified using TLDs and films imbedded in an anthropomorphic H&N phantom. PACS numbers:

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Volumetric modulated arc therapy treatment planning assessment for low-risk prostate cancer in radiotherapy

Cited by 6 publications

References 0 publications

Evaluation of three dimensional conformal radiation therapy of oesophageal cancer: a dosimetric study

Evaluation of three dimensional conformal radiation therapy of oesophageal cancer: a dosimetric study

RapidArc treatment planning quality assurance using electronic portal imaging device for cervical cancer

Dose verification of volumetric-modulated arc therapy using one-dimensional and two-dimensional dosimeters

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