Volumetric Properties of the Nucleoside Thymidine in Aqueous Solution at T = 298.15 K and p = (10 to 100) MPa

Volumetric Properties of the Nucleosides Adenosine, Cytidine, and Uridine in Aqueous Solution at T = (288.15 and 313.15) K and p = (10 to 100) MPa

“…The values for gH2O(p) over the range p = (0.1 to 100) MPa were evaluated using the literature data given in Table 3. For consistency with our previous work [10,12,27], the sound speeds were calculated using the equation reported by Chen and Millero [28]. It is worth reiterating [29] that the sound speeds for water at the nominal temperature of 300 K calculated using the equation reported by Chen and Millero differ from those in the comprehensive article by Wagner and Pruss [30] by less than 0.01% at pressures up to 20 MPa and by less than 0.03% at the higher pressures used in this study.…”

“…It is convenient to combine the results obtained herein with those for T = 298.15 K obtained previously [10] and hence use 3D diagrams to display the pressure and temperature dependences of the partial molar volumes and the partial molar isothermal compressions at infinite dilution for the three nucleosides at T = 298.15 K actually changes sign at about p = 90 MPa [10] so the value of V2 o is essentially constant at the higher pressures used in this study (see Various semi-empirical models are often used to rationalize the volumetric properties of small organic solutes in aqueous solution [37][38][39]. In previous work [10,20,27], we used a model [37] that involves an interpretation of hydration effects based on the relationship:…”

Volumetric Properties at High Pressures of the Nucleosides Inosine, 2′-Deoxyinosine, and 2′-Deoxyguanosine and the Volumetric Properties of Guanosine Derived Using Group Additivity Methods

“…The measured sound speeds for aqueous solutions of inosine, 2′-deoxyinosine, and 2′-deoxyguanosine at T = 298.15 K and p = (10.0 to 100.0) MPa are given in Table . In previous work, ,, we chose to analyze the quantity γ/ u 2 by weighted least-squares using a third-order polynomial in the independent variable ( p – 0.1). For the sytems studied previously, integration of this polynomial using eq gave solution densities from which quite satisfactory thermodynamic properties were derived.…”