Voluntary Control of Cough

Lee, P. C. L.; Cotterill-Jones, C.; Eccles, Ronald

doi:10.1006/pupt.2002.0365

Cited by 83 publications

(54 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…First, V-CPF and IV-CPF employ different pathways to generate coughing. [22][23][24][25] The voluntary cough, which is controlled by the cerebral cortex, is initiated by irritation or voluntary action and can be inhibited by conscious patients. If a patient is told to do so, voluntary coughing can be depressed by 90% when capsaicin is inhaled.…”

Section: Discussionmentioning

confidence: 99%

“…If a patient is told to do so, voluntary coughing can be depressed by 90% when capsaicin is inhaled. 22,26 On the other hand, the involuntary cough is controlled by the brainstem and is only initiated by irritation when the stimulus reaches a reflex threshold. Moreover, involuntary cough strength is associated with the intensity of the irritation.…”

Section: Discussionmentioning

confidence: 99%

“…However, it also can be depressed in conscious patients. 22,26 In this study, the involuntary cough was stimulated by 2 mL of normal saline, and different subjects may have had different reflex thresholds. We found that The Յ 25th, 25th through 50th, 50th through 75th, and Ͼ 75th percentile of the V-CPF were classified as lower quartile, third quartile, second quartile, and upper quartile, respectively.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Voluntary Is Better Than Involuntary Cough Peak Flow for Predicting Re-Intubation After Scheduled Extubation in Cooperative Subjects

et al. 2014

View full text Add to dashboard Cite

BACKGROUND:In this study, we compared the predictive accuracy of voluntary cough peak flow (V-CPF) and involuntary cough peak flow (IV-CPF) for re-intubation in mechanically ventilated subjects. METHODS: Endotracheally intubated patients who passed a spontaneous breathing trial and assessment of readiness for extubation were enrolled. Before extubation, V-CPF and IV-CPF were measured. Re-intubation was recorded at 72 h after extubation. RESULTS: A total of 115 extubations in 106 cooperative subjects (including 9 subjects with second extubation) and 5 extubations in 5 uncooperative subjects were recorded. At 72 h, 20 (17.4%) and 1 (25%) instances of re-intubation occurred in cooperative and uncooperative subjects, respectively. In cooperative subjects, those who had been successfully extubated had higher V-CPF than re-intubated subjects

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Voluntary Is Better Than Involuntary Cough Peak Flow for Predicting Re-Intubation After Scheduled Extubation in Cooperative Subjects

et al. 2014

View full text Add to dashboard Cite

show abstract

“…Limited information is available on cerebral mechanisms involved in volitional cough and cough suppression in awake humans (Lee et al, 2002;O'Connell, 2002), although human experience demonstrates that volitional cough generation and suppression is possible. In the cat, Kase found electrical stimulation in the suprasylvian gyrus could initiate cough (Kase et al, 1984).…”

Section: Coughmentioning

confidence: 99%

Central nervous system control of the laryngeal muscles in humans

Ludlow

2005

Respiratory Physiology & Neurobiology

143

104

View full text Add to dashboard Cite

Laryngeal muscle control may vary for different functions such as: voice for speech communication, emotional expression during laughter and cry, breathing, swallowing, and cough. This review discusses the control of the human laryngeal muscles for some of these different functions. Sensorimotor aspects of laryngeal control have been studied by eliciting various laryngeal reflexes. The role of audition in learning and monitoring ongoing voice production for speech is well known; while the role of somatosensory feedback is less well understood. Reflexive control systems involving central pattern generators may contribute to swallowing, breathing and cough with greater cortical control during volitional tasks such as voice production for speech. Volitional control is much less well understood for each of these functions and likely involves the integration of cortical and subcortical circuits. The new frontier is the study of the central control of the laryngeal musculature for voice, swallowing and breathing and how volitional and reflexive control systems may interact in humans.

show abstract

“…A peculiar aspect of the cough reflex is the high degree of voluntary (cortical) control to which it is subjected, so that all possible cough patterns can be mimicked and the frequency and intensity of spontaneous cough be modulated up to complete suppression [2]. Accordingly, in physiology textbooks cough is defined as a respiratory expulsive reflex consisting of three phases, with a preparatory inspiration followed by compressive and expulsive phases [3].…”

Section: Introductionmentioning

confidence: 99%

Voluntary and reflex cough: Similarities and differences

Magni¹,

Chellini²,

Lavorini³

et al. 2011

Pulmonary Pharmacology & Therapeutics

View full text Add to dashboard Cite

Cough is defensive airway reflex subjected to a high degree of cortical control. Not surprisingly, all cough motor patterns can be mimicked and reflex cough be inhibited up to complete suppression, at least to a certain extent. Reflex cough differentiates from other airway reflex responses for its characteristic 3-phase motor pattern, and such pattern is maintained when coughing is produced voluntarily. Despite these and some other similarities, voluntary and reflex cough differ in many important respects, suggesting different neural control of the respiratory and non-respiratory musculature implicated in the generation of the cough modalities. This paper focuses the motor features that differentiate voluntary and reflex cough efforts, and highlights the importance of functional assessment of coughing in the diagnostic workup of respiratory and extra-respiratory diseases affecting the production of voluntary and reflex cough.

show abstract

Voluntary Control of Cough

Cited by 83 publications

References 18 publications

Voluntary Is Better Than Involuntary Cough Peak Flow for Predicting Re-Intubation After Scheduled Extubation in Cooperative Subjects

Voluntary Is Better Than Involuntary Cough Peak Flow for Predicting Re-Intubation After Scheduled Extubation in Cooperative Subjects

Central nervous system control of the laryngeal muscles in humans

Voluntary and reflex cough: Similarities and differences

Contact Info

Product

Resources

About