“…Older generations of HES with substitution ratios of 0.5, 0.6, and 0.7 are known as penta-, hexa-, and hetastarches, respectively. 8 Newer generation tetrastarches are derived from two sources. The raw material is either waxy maize starch in 6% HES 130/0.4 (Voluven® or Volulyte®, Fresenius Kabi, Bad Homburg, germany) or potato starch in 6% HES 130/0.42 (e.g., Venofundin® or tetraspan®, B. Braun Melsungen, germany; VitaHES® or Vitafusal®, Serumwerk Bernburg, germany; PlasmaVolumeRedibag®, Baxter, Unterschleißheim, germany), and some including Martin et al 7 believe that maize-and potatoderived 6% HES 130 are not biologically equivalent.…”