Von der Präzisionssynthese von Blockcopolymeren zu Eigenschaften und Anwendungen von funktionellen Nanopartikeln

Li, Xiao; Iocozzia, James; Chen, Yihuang; Zhao, Shiqiang; Cui, Xun; Wang, Wei; Yu, Haifeng; Lin, Shaoliang; Lin, Zhiqun

doi:10.1002/ange.201705019

Cited by 14 publications

(2 citation statements)

References 186 publications

(114 reference statements)

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“…Snaith et al , prepared the synthesis of mesoporous TiO 2 film using as photoanodes of dye-sensitized solar cells. Steiner et al reported a series of inorganic materials in self-assembled polymeric templates for various applications. − Lin et al − innovatively synthesized monodisperse nanocrystal with various compositions and architectures by using starlike copolymers with well-defined structures and narrow molecular weight distributions as nanoreactors.…”

Section: Introductionmentioning

confidence: 99%

Formation of Diverse Ordered Structures in ABC Triblock Terpolymer Templated Macroporous Silicas

et al. 2018

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The macroporous silica synthesis system with the ABC triblock terpolymer poly(ethylene oxide)-block-polystyrene-block-poly(tert-butyl acrylate) (denoted as OSA) as template and tetraethyl orthosilicate as silica source under acidic conditions in a mixture solvent of tetrahydrofuran and H 2 O has been investigated, and two synthesis−field phase diagrams are plotted. Eight different structures varied from normal-phase (oil in water) cage-type (n-C), normal-phase 2D hexagonal (n-H), and lamellar (L) to unique inverse-phase (water in oil) hyperbolic-surface (i-HS) structures, including the shifted double-diamond (i-SDD), single-gyroid (i-SG), and shifted double-primitive (i-SDP), inverse-phase 2D hexagonal (i-H) and inverse-phase micellar (i-M) structures, have been formed by varying the degree of polymerization of the hydrophobic blocks in OSA. From the two-component phase diagram, it can be concluded that the macroporous structures formation is affected by the packing parameter p and the segregation product (χN) of the hydrophilic and hydrophobic blocks. With an increase in p, the structures n-C and n-H were found in the range of low χN, whereas the structures i-HS, i-H, and i-M were found in the range of higher χN, while L is in between. In the threecomponent phase diagram, different volume fraction ratios (VFR) of the hydrophobic/hydrophilic block (S/O, A/O) and those of hydrophobic/hydrophobic block (S/A) in this co-assembly system divided the resultant ordered structures in various regions. The n-C, n-H, and L structures were found in low VFRs of S/O and A/O; i-H and i-M structures were formed in high VFRs of S/O and A/O. The formations of the i-HS structures including i-SDD, i-SDP, and i-SG are depending on low VFRs regions of S/ O and S/A with similar packing parameter.

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Section: Introductionmentioning

confidence: 99%

Formation of Diverse Ordered Structures in ABC Triblock Terpolymer Templated Macroporous Silicas

et al. 2018

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“…[6][7][8][9][10][11][12] Among these, block copolymers provide unique advantages because of flexibility in structure variations, well-defined compartmentalized segments to form higher ordered structures and stable encapsulation of hydrophobic drug molecules. [13][14][15][16][17] But these systems also exhibit inefficient and incomplete drug release, which directly impedes their potential. Molecular release from block copolymer assemblies can be broadly classified into two approaches.…”

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confidence: 99%

Cellular‐ and Subcellular‐Targeted Delivery Using a Simple All‐in‐One Polymeric Nanoassembly

et al. 2020

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Nanocarrier‐mediated drug delivery is a promising strategy to maximize the power of chemotherapy and minimize side effects. However, current approaches show insufficient drug‐loading capacity and inefficient drug release, and require complex modification processes. Attempts to enhance one of these features often compromise other merits. We describe here a block copolymer assembly system that combines desirable characteristics. The design of self‐immolative and crosslinkable hydrophobic moieties offer stable and high encapsulation. Redox‐triggerable polymer self‐immolation promotes drug release by switching the hydrophobic core into completely hydrophilic chains. The reactive amine handles, presented on their surface, allow “plug to direct” modification with targeting ligands. Functionalized nanoassemblies have been programmed to target specific subcellular compartments. The simplicity, versatility, and efficacy of the system open up possibilities for an all‐in‐one delivery system.

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Partikel für Partikel – elektrochemische Einschlagsexperimente zur Synthese oberflächenimmobilisierter Goldnanopartikel für die Elektrokatalyse

et al. 2019

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Wird emonstrieren die sukzessive elektrochemische Umsetzung einzelner HAuCl 4 -gefüllter Nanoreaktoren auf einer Kohlefaserelektrode zur Funktionalisierung mit Nanopartikeln (NP). Dabei kçnnen Grçße und Anzahl der einzeln abgeschiedenen NP während des Prozesses kontrolliert werden. Zunächst werden Mizellenv on enger Grçßenverteilung mit Metallsalz beladen. Der sporadischeEinschlag dieser Mizellen auf einer polarisierten Elektrode führt zur Reduktion der Metallionen und es entsteht ein einzelner NP.Die während eines Einschlags übertragene Ladung wird gemessen und ermçglichtdie operando-Grçßenbestimmung des gebildeten NP. Wirz eigen dies fürd ie Beladung von zylindrischen Kohlefaserelektroden mit 25 AE 7nmg roßen AuNP,d ie bereits bei niedrigen Katalysatorbeladungen eine hervorragende Leistung fürd ie Sauerstoffreduktion (ORR) zeigen. Diese Form der Nanoeinschlagsmethode wird daher als neuer Wegz un anopartikelmodifizierten Elektroden mit effektiver Katalysatorausnutzung vorgestellt.

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Von der Präzisionssynthese von Blockcopolymeren zu Eigenschaften und Anwendungen von funktionellen Nanopartikeln

Abstract: This is the author manuscript accepted for publication and has undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record.

Cited by 14 publications

References 186 publications

Formation of Diverse Ordered Structures in ABC Triblock Terpolymer Templated Macroporous Silicas

Formation of Diverse Ordered Structures in ABC Triblock Terpolymer Templated Macroporous Silicas

Cellular‐ and Subcellular‐Targeted Delivery Using a Simple All‐in‐One Polymeric Nanoassembly

Partikel für Partikel – elektrochemische Einschlagsexperimente zur Synthese oberflächenimmobilisierter Goldnanopartikel für die Elektrokatalyse

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