1989
DOI: 10.1016/0049-3848(89)90174-6
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Von Willebrand factor antigen and dental infections

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Cited by 48 publications
(31 citation statements)
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“…70,71 In addition, it was shown that high levels of factor VIII activity and its cofactors in the coagulation pathway were associated with poor dental health, linking chronic dental infections with increased thrombogenicity. 72 The studies reviewed above provide a conceivable explanation for the emerging correlation between periodontitis and cardiovascular diseases. In this scheme, P gingivalis proteases would have an indirect role as factors aggravating or sustaining chronic inflammation.…”
Section: Discussionmentioning
confidence: 99%
“…70,71 In addition, it was shown that high levels of factor VIII activity and its cofactors in the coagulation pathway were associated with poor dental health, linking chronic dental infections with increased thrombogenicity. 72 The studies reviewed above provide a conceivable explanation for the emerging correlation between periodontitis and cardiovascular diseases. In this scheme, P gingivalis proteases would have an indirect role as factors aggravating or sustaining chronic inflammation.…”
Section: Discussionmentioning
confidence: 99%
“…La periodontitis puede generar problemas hemostáticos, tales como el aumento del fibrinógeno plasmático, del recuento de glóbulos blancos, de la proteína C reactiva y de la viscosidad de la sangre (Mattila et al, 1989). Es compleja porque además posee bacterias como Streptoccocus viridans, responsable de la endocarditis bacteriana (Lang & Karring, 1994), o la Porphyromonas gingivalis, causante del aumento de moléculas de adhesión que provoca la liberación de citoquinas y quimioquinas (Deshpande et al, 1999).…”
Section: Resultados Y Discusiönunclassified
“…Many past studies confirmed that myocardial infarction is the most frequently found systemic disease in patients suffering from different forms o f periodontal diseases. These studies have identified statistically significant associations between established periodontitis and cardiovascular diseases Briggs, 2006;Buhlin, Gustafsson, Hakansson, & Klinge, 2002;Dirk Ziebolzl et al, 2011;Guillermo & Machuca, 2012;Mattila et al, 1989;Rehman & Salama, 2004;Stein et al, 2011;Willershausen, Kasaj, Willershausen & Zahorka, 2009). Similarly, a positive association has been reported between AMI, and tooth extraction due to infection or periodontal diseases including periapical lesions as well as pericoronitis (Lise, Ingar & Kjersti, 2011;Mattila et al, 1995;Spivakovsky, 2012).…”
Section: Infection-induced Perturbations In Lipid Profiles As Per Thmentioning
confidence: 99%
“…Despite the presence o f a large body of literature investigating the link between oral and cardiovascular diseases, only a few studies investigated the particular link between periodontal diseases and acute myocardial infarction. For the first time, in late 80's, a case control study (Mattila et al, 1989) reported a highly significant positive association between poor dental health and acute myocardial infarction. The observed association was independent o f the traditional risk factors for heart disease.…”
Section: Infection-induced Perturbations In Lipid Profiles As Per Thmentioning
confidence: 99%
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