2021
DOI: 10.1016/j.msec.2020.111508
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Vorapaxar-modified polysulfone membrane with high hemocompatibility inhibits thrombosis

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Cited by 13 publications
(8 citation statements)
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“…It was found that the hydrophobic surface character of these biomaterials could lead to the adherence of plasma proteins to the hydrophobic surfaces forming plasma clotting [ 43 ]. In the last decade, many materials were studied for their hemocompatibility, such as polyvinyl alcohol (PVA) [ 43 , 44 ], cellulose triacetate (CTA) [ 43 , 45 ], polymethylmethacrylate (PMMA) [ 38 , 46 ], polyacrylonitrile (PAN) [ 47 , 48 ], polysulfone (PSF) [ 9 , 20 , 49 ], polyethersulfone (PES) [ 43 , 50 , 51 ] and polyamide (PA) [ 46 , 52 ]. Polysulfone (PSF) is a thermoplastic polymer used in the biomedical field as a dialysis membrane due to physicochemical properties, such as thermal stability, chemical resistance, decent mechanical strength, great processability and biocompatibility [ 43 ].…”
Section: Polysulfone Functionalized Membranes For Hemodialysismentioning
confidence: 99%
See 3 more Smart Citations
“…It was found that the hydrophobic surface character of these biomaterials could lead to the adherence of plasma proteins to the hydrophobic surfaces forming plasma clotting [ 43 ]. In the last decade, many materials were studied for their hemocompatibility, such as polyvinyl alcohol (PVA) [ 43 , 44 ], cellulose triacetate (CTA) [ 43 , 45 ], polymethylmethacrylate (PMMA) [ 38 , 46 ], polyacrylonitrile (PAN) [ 47 , 48 ], polysulfone (PSF) [ 9 , 20 , 49 ], polyethersulfone (PES) [ 43 , 50 , 51 ] and polyamide (PA) [ 46 , 52 ]. Polysulfone (PSF) is a thermoplastic polymer used in the biomedical field as a dialysis membrane due to physicochemical properties, such as thermal stability, chemical resistance, decent mechanical strength, great processability and biocompatibility [ 43 ].…”
Section: Polysulfone Functionalized Membranes For Hemodialysismentioning
confidence: 99%
“…Further, in functionalization, functional groups could be used, such as small compounds that could be linked directly to the PSF or by using different linker molecules and macromolecules by the grafting of chemical functions onto an aromatic ring followed by immobilization using a linker molecule [ 49 , 55 ]. The PSF does not have any vacant functional groups and in order to perform functionalization, additional functional groups must be added by grafting onto the aromatic rings, such as the introduction of a sulfonate group into the polymer structure through electrophilic substitution via sulfonation [ 47 ]. The addition of the sulfonic group increases the membrane’s permeability, hydrophilicity, hemocompatibility, anti-fouling behavior and antimicrobial properties [ 56 , 57 ].…”
Section: Polysulfone Functionalized Membranes For Hemodialysismentioning
confidence: 99%
See 2 more Smart Citations
“…There was a lot of heparinoid synthesis going on at present. [21][22][23][24] Zhao et al 25 discovered that modified polyethersulfone (PES) membranes are having both carboxyl and sulfonic acid groups performed better in terms of hemocompatibility than modified PES membranes containing solely sulfonic acid groups. Tu et al 26 created a modified SHPCS-AA-PSF membrane by covalently grafting acrylic acid (AA) and sulfonated hydroxypropyl chitosan (SHPCS) onto the polysulfone (PSF) membrane surface.…”
Section: Introductionmentioning
confidence: 99%