“…A variety of clinical applications for wIRA has been described (reviewed in Hoffmann, 2007, 2017a), like improvement of wound healing in acute and chronic wounds (Hartel et al, 2007; von Felbert et al, 2007; Hoffmann, 2009; Daeschlein et al, 2012; Hoffmann et al, 2016), application in sports medicine and physiotherapy (Vaupel et al, 1995; Hoffmann, 2002), treatment of Morbus Bechterew (Falkenbach et al, 1996) or weight loss (Möckel et al, 2006), in the neonatology field (Singer et al, 2000; Löwe and Singer, 2008), for treatment of scleroderma lesions (Von Felbert et al, 2007, 2011), swallowing disorders and hypersalivation (Hoffmann, 2017b), therapy of recurrent breast cancer (Notter et al, 2017) and superficial tumors (Vaupel et al, 2018), or as a treatment method for actinic keratosis in combination with photodynamic therapy (PDT) (Von Felbert et al, 2010; Giehl et al, 2014). Moreover, wIRA can promote the penetration of topically applied substances (Otberg et al, 2008) and is also attractive for cosmetics and wellness applications (Piazena and Kelleher, 2010; Jung and Grune, 2012).…”