Voters in St. Louis, Missouri, faced unprecedented challenges amid two critical elections during the 2020 election season. Voters were to determine if the state should expand access to Medicaid as well as decide the next President of the United States. The emergence COVID-19 complicated voter mobilization efforts as public health restrictions were implemented limiting access to voters. Additionally, the state quickly introduced new policies and rules that created confusion among voters. This study presents an in-depth qualitative case study of voter mobilization efforts in St. Louis by drawing on semi-structured interviews with 28 participants who engaged in voter mobilization within poverty-impacted communities in St. Louis City and St. Louis County. Subjects identified how they shifted tactics to allow for the health and safety of mobilizers and potential voters. Findings from this study provide evidence on how decision-making within the context of mobilization changes during wide scale social and political shocks.