VP29.01: A case of fetal achondroplasia: ultrasonographic features

Abstract

Objectives: To offer chromosomal microarray in fetuses with structural abnormalities. Methods: A total of 100 subjects was recruited subjected to CMA testing in fetuses with structural abnormalities in a single centre. Results: The number of cardiac anomalies were 18%, thoracic 13%, Renal were 11%, severe onset growth restriction were 10%, CNS abnormalities were 16%, GIT and were 19% and increased Nuchal Translucency were 13%. The proposed CMA test was significant (p < 0.005) and effective, identified chromosomal anomalies with the pick-up rate of the overall 12%. This led to efficient identification of clinically significant sub-chromosomal deletions or duplications, for structurally abnormal pregnancies as diagnosed on USG. Conclusions:This technology open doors for deeper changes in screening policies and recommendations for prenatal care and could be the standard of care for fetuses with structural abnormalities. VP28.16Application of polymerase chain reaction for embryo gender determination using blood of pregnant women