Vulvar fibroadenoma: a common neoplasm in an uncommon site

Abstract

Vulvar fibroadenomas are sporadic lesions informed in the literature and a controversy about origin has been discussed widely. We report a case of a 19 years old woman with a large slow growing mass in the right labia majora with the final diagnosis of fibroadenoma with mammary tissue surrounding it and positive hormone receptors. In this case, we support the origin in ectopic mammary tissue.

Prepubertal vulval fibroma with a coincidental ectopic breast fibroadenoma: Report of an unusual case with literature review

“…We herein summarize the English language literature about ectopic breast fibroadenoma since the year 2000 (Table 1). Our report increases the number of cases that support the origin of ectopic breast tissue as previously reported 22 . Follow up was mentioned in four articles, ranging from 9 months to 3 years (Table 1).…”

“…Our report increases the number of cases that support the origin of ectopic breast tissue as previously reported. 22 Follow up was mentioned in four articles, ranging from 9 months to 3 years (Table 1). Recurrence may occur and was thought to be due to an incomplete excision.…”

Ectopic Breast Tissue in the Vagina Detected at the Median Episiotomy Site

“…These glands are called mammary-like anogenital glands which are present in the anogenital region and are thought to be adnexal glands similar to mammary glands. Van der Putte's theory also states that the formation of these lesions does not require the existence of normal breast tissues [4,8,9]. In 2006, Atwal published a case of previously documented supernumerary mammary tissue-originating vulvar fibroadenoma, describing a lesion that histopathologically mimicked a fibroadenoma with positive estrogenic receptors on immunohistochemistry and with healthy mammary tissues surrounding the lesion [5].…”

Fibroadenomas of anogenital mammary-like glands: from embryogenesis anomaly to apocrine origin

“…Aberrant mammary tissue occurs in 1-6% of the population, being more prevalent in women in axilla and in upper umbilical scars location [3,4,8]. Supernumerary breasts or nipples, polymastia and polythelia may develop from extramammary buds and rarely from tissue displaced from these ridges.…”

“…Adenocarcinoma may also arise in vulvar mammary-like glands and has to be differenti- NA -not available ated from conventional cutaneous adenocarcinoma of apocrine and eccrine origin and metastatic mammary carcinoma [8,21,28]. Extralesional tissue documentation may certify the development of the lesions within mammary-like glands [3,6,20,25].…”