Vulvar syringoma: A clinicopathologic and immunohistologic study of 18 patients and results of treatment

Huang, Yu‐Huei; Chuang, Ya‐Hui; Kuo, Tseng‐Tong; Yang, Lan-Yan; Hong, Hong‐Shang

doi:10.1067/mjd.2003.285

Cited by 93 publications

(107 citation statements)

References 18 publications

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“…54,55 Originally described in 1874 by Kaposi, vulvar involvement was not reported until 1971 and has been regarded as a rare manifestation. 55 Since then, isolated cases and small case series of syringomas involving the genital region have been reported.…”

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confidence: 99%

“…55 Since then, isolated cases and small case series of syringomas involving the genital region have been reported. [54][55][56][57][58][59][60][61][62][63][64][65][66][67] In a Taiwanese series of 18 cases of vulvar syringoma, lesions were most common in women during the third decade, most often (11 of 18; 61%) presenting as multiple, flesh-colored or brownish papules on the labia majora. 54 Three (17%) presented with discrete, whitish cystic papules.…”

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confidence: 99%

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Vulvar Adnexal Lesions: A 32-Year, Single-Institution Review From Massachusetts General Hospital

Baker

Selim

Hoang

2013

Archives of Pathology &Amp; Laboratory Medicine

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Context.-Because the skin and modified mucosal surfaces of the vulvar region contain dense apocrine glands and anogenital mammary-like glands, in addition to eccrine glands and folliculosebaceous units, benign as well as malignant lesions derived from these adnexal structures are, not surprisingly, found in the vulva. However, their incidence occurring in the vulva has not been reported, to our knowledge.Objective.-To determine the incidence of various vulvar adnexal lesions.Design.-We performed a retrospective review of the cases at our institution.Results.-A total of 189 vulvar adnexal lesions were identified. Most of these lesions were benign (133 of 189; 70%), with hidradenoma papilliferum being the most common, followed by syringoma and various types of cysts. Rare cases of tubular adenoma, poroma, spiradenoma, hidradenoma, cylindroma, sebaceoma, and trichoepithelioma were identified. Malignant adnexal neoplasms comprised the remaining 30% (56 of 189) of the cases. Extramammary Paget disease was the most common (49 of 56), and 29% (14 of 49) demonstrated an invasive component. Rare cases of basal cell carcinoma, sebaceous carcinoma, apocrine carcinoma, adenoid cystic carcinoma, and spiradenocarcinoma were identified.Conclusions.-In this retrospective review, we identified several benign entities that have not been previously reported on the vulva, namely pilomatricoma, poroma, spiradenoma, and sebaceoma. Hidradenoma papilliferum and extramammary Paget disease were the most common benign and malignant adnexal neoplasms, respectively. The spectrum of various vulvar adnexal lesions appears to reflect the frequency of the underlying glandular elements.

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Vulvar Adnexal Lesions: A 32-Year, Single-Institution Review From Massachusetts General Hospital

Baker

Selim

Hoang

2013

Archives of Pathology &Amp; Laboratory Medicine

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“…In a review of 18 cases, two other clinical appearances of vulvar syringoma have been described: milium-like whitish cystic papules and lichenoid papules 2 .…”

Section: Discussionmentioning

confidence: 99%

“…Th ey commonly occur in the lower eyelid and upper malar areas, appearing less frequently in the upper lip, axillae, extremities, buttocks, chest, abdomen, or thigh with the involvement of the vulva being rare 1,2 . Vulvar syringomas typically present as multiple, one to two mm, fl esh-colored to yellow papules arranged bilateral and symmetrical on the major labia, however solitary lesions have also been reported 1,3 .…”

Section: Introductionmentioning

confidence: 99%

Vulvar syringoma in a premenopausal woman: A case report

Üstüner¹,

Balık²,

Güçer³

et al. 2015

Kafkas J Med Sci

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“…Some ducts present characteristic small, comma-shaped epithelial cell tails that resemble a tadpole. Normally, the ducts are lined with 2 rows of epithelial cells and may be filled with eosinophilic material [2,3]. Response to treatment is usually unsatisfactory.…”

Section: Introductionmentioning

confidence: 99%

Isolated Vulval Syringoma Presenting as Hyperpigmented Papules: Report of a Rare Presentation

2016

J turk acad dermatol

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Observation: Syringomas are benign tumours of sweat glands that commonly present over face. Syringomas appear as small, multiple, skin-coloured-to-yellowish papules occuring commonly over upper and lower eyelids, malar areas; infrequently over the axillae, neck, chest, upper arms, and abdomen. The incidence of vulvar syringoma is relatively rare. Syringomas are commonly seen in adolescence. We report a case of isolated vulval syringoma in a middle aged lady presenting with an altered morphology.

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Vulvar syringoma: A clinicopathologic and immunohistologic study of 18 patients and results of treatment

Cited by 93 publications

References 18 publications

Vulvar Adnexal Lesions: A 32-Year, Single-Institution Review From Massachusetts General Hospital

Vulvar Adnexal Lesions: A 32-Year, Single-Institution Review From Massachusetts General Hospital

Vulvar syringoma in a premenopausal woman: A case report

Isolated Vulval Syringoma Presenting as Hyperpigmented Papules: Report of a Rare Presentation

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