Vulvar Verruciform Xanthoma

Fite, C.; Plantier, Fran çoise; Dupin, Nicolas; Avril, Marie-Fran çoise; Moyal‐Barracco, Micheline

doi:10.1001/archdermatol.2011.113

Cited by 46 publications

(20 citation statements)

References 48 publications

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“…She then had surgical removal, but the removal was incomplete, and the verruciform xanthoma recurred 2 years later [43]…”

Section: Introductionmentioning

confidence: 99%

“…Oliveira et al proposed that verruciform xanthomas are formed by an autoimmune reaction inducing apoptosis of epithelial cells, similarly to lichen planus [84]. This is supported by multiple cases of verruciform xanthomas reported in association with lichen planus [43, 85]. …”

Section: Introductionmentioning

confidence: 99%

“…Vulvar lesions have been found in association with CHILD syndrome [44, 47, 49, 52, 59, 60], fibroepithelial polyp [57], leiomyomatosis of uterus [55], lichen planus [43], lichen sclerosus [43, 54], lymphangioma circumscriptum with severe lymphedema [50], radiodermatitis [43], and vulvar Paget’s disease [43]. …”

Section: Introductionmentioning

confidence: 99%

“…The verruciform xanthomas are cured by complete excision; however, cases of recurrence have been described [13, 43, 76]. One case of recurrence occurred when the lesion was not completely excised [43].…”

Section: Introductionmentioning

confidence: 99%

“…One case of recurrence occurred when the lesion was not completely excised [43]. CO 2 laser ablation resulted in the recurrence in two cases of vulvar lesions [43, 76].…”

Section: Introductionmentioning

confidence: 99%

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Vegas (Verruciform Genital-Associated) Xanthoma: A Comprehensive Literature Review

Stiff

Cohen

2016

Dermatol Ther (Heidelb)

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IntroductionVerruciform xanthoma is a wart-like benign lesion. The classic histologic appearance consists of foamy histiocytes within elongated dermal papillae and epithelial acanthosis. The lesion most commonly occurs in the oral cavity, but has been reported in extra-oral sites such as the penis, scrotum, and vulva. The clinical and histologic characteristics of verruciform genital-associated (Vegas) xanthomas of the penis, scrotum, and vulva are reviewed.MethodsPubMed was used to search the following term: verruciform xanthoma. The relevant papers were obtained and reviewed.ResultsThere have been 193 cases of genital-associated verruciform xanthomas. There were 164 in men and 29 in women. Similar to verruciform xanthomas of the oral mucosa, they presented as asymptomatic lesions, demonstrated foam cells in the dermal papillae, and were typically managed successfully with surgical excision.ConclusionVerruciform xanthoma is a benign lesion characterized by a wart-like growth that is most commonly seen in the oral mucosa. Verruciform xanthomas of the genital region have been coined Vegas xanthomas. Vegas xanthomas have been reported in association with a variety of diseases, as well as in healthy individuals. Biopsy is required for diagnosis, and complete surgical excision is typically curative.

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“…She then had surgical removal, but the removal was incomplete, and the verruciform xanthoma recurred 2 years later [43]…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…One case of recurrence occurred when the lesion was not completely excised [43]. CO 2 laser ablation resulted in the recurrence in two cases of vulvar lesions [43, 76].…”

Section: Introductionmentioning

confidence: 99%

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