Vγ6⁺ γδ T cells are critical for protection against infection by Escherichia coli in mice

Abstract

γδ T cells producing IL‐17A (γδTh17 cells) are known to be involved in peritonitis induced by Escherichia coli infection in mice. In vivo treatment with Vγ6‐specific mAb (1C10‐1F7) significantly hampered resolution of E. coli infection. Thus, Vγ6+γδTh17 cells mainly contributed to protection against E. coli infection.