W1638: The Study of Magnifying Endoscopy for the Diagnosis of Portal Hypertensive Gastropathy

Assef, Maurício Saab; Valentino, Wagner; Nakamura, Romeu; Camunha, Marco; Colaiácovo, Rogério; Rossini, Lucio G.

doi:10.1016/j.gie.2010.03.1046

Cited by 2 publications

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“…In 2008, Assef et al 6 showed an increased frequency of elevated erosive gastritis covered with fibrin, affecting the gastric antrum of patients with PH (37.5%). Among these, 16.7% had no endoscopic diagnosis of PHG, while 50% had mild PHG and 33.3% had severe PHG.…”

Section: Resultsmentioning

confidence: 99%

“…[1][2][3][4][5] This wide variation is likely due to the challenges associated with making a correct endoscopic diagnosis, especially for milder forms or those not associated with bleeding. 6 The three most accepted and used classifications (McCormack, 7 New Italian Endoscopy Club 8 and Baveno Consensus 9 ) are still widely debated, but it is clear that the simplest classification is still the most adopted with the highest consensus among endoscopists. 10 In medical practice, there is a correlation between endoscopic findings of PHG and the presence of elevated gastric antral erosions in PH patients.…”

Section: Introductionmentioning

confidence: 99%

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Elevated Gastric Antrum Erosions in Portal Hypertension Patients: Peptic Disease or Mucosal Congestion?

Conejo

Fracassi

Assef

et al. 2017

Korean J Gastroenterol

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Background/Aims: Portal hypertension (PH) is a syndrome characterized by chronic increase in the pressure gradient between the portal vein and inferior vena cava. Previous studies have suggested an increased frequency of antral elevated erosive gastritis in patients with PH, as well as an etiologic association; however, there has not been any histological evidence of this hypothesis to date. Our aim was to evaluate the histological features found in elevated antral erosions in patients with portal hypertension. Methods: Sixty-nine patients were included; 28 with and 41 without PH. All patients underwent endoscopy, and areas with elevated antral erosion were biopsied. Results: In the PH group, 24 patients had inflammatory infiltration with or without edema and vascular congestion, and 4 patients had no inflammation. In the group without PH, all patients showed inflammatory infiltration of variable intensity. There was no statistical significance between the two groups in the presence of Helicobacter pylori. There as a histological similarity between the two groups, if PH patients without inflammation were excluded; however, more edema and vascular congestion were observed in the PH group (p=0.002). Conclusions: The findings show that elevated antral erosions in patients with PH have more evident edema and vascular congestion in addition to lymphocytic infiltration. (Korean J Gastroenterol 2017;69:278-282)

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Section: Resultsmentioning

confidence: 99%