W1796 Differential Diagnosis of Intrahepatic Biliary Cystadenoma and Hepatic Simple Cyst: Significance of Cystic Fluid Analysis and Radiologic Finding

Differentiating Simple Hepatic Cysts from Mucinous Cystic Neoplasms: Radiological Features, Cyst Fluid Tumour Marker Analysis and Multidisciplinary Team Outcomes

“…We did not find evidence that CA 19-9, CEA or CA 125 were able to differentiate between MCN and SC, which is consistent with previous studies [4,11,19] . However, it is important to note that the patients with SC in this study represent a selected group of patients with large cysts causing symptoms or displaying suspicious radiological features.…”

“…MCNs have a reported incidence of one in 20,000-100,000 and account for 4.6% of intrahepatic cysts of biliary origin [8][9][10][11] . Due to lack of disease-specific biochemical or radiological features, accurate pre-operative diagnosis is often challenging.…”

Ruptured Biliary Cystadenoma Managed by Angiographic Embolization and Interval Partial Hepatectomy

“…Both segmental hepatic artery branches were embolized to stasis with particles 1949-1953 1951 lesions. More recently, however, these findings have been disputed by Choi et al [15], who noted cyst fluid CA 19-9 levels to be equally elevated in 17 patients with biliary cystadenomas and 14 patients with simple hepatic cysts (mean, 2,999,286 U/ml vs. 180,787 U/ml, P = 0.406). The current role of cyst fluid CA 19-9 in differentiating biliary cystadenomas from simple hepatic cysts, therefore, remains undetermined.…”

“…Initial reports suggested that serum CA 19-9 may be elevated in patients with biliary cystadenomas and cystadenocarcinomas [13,14]. Specific attention has recently been focused on measuring CA 19-9 levels in the cyst fluid of these lesions [15][16][17]. Koffron et al [17] demonstrated that cyst fluid CA 19-9 was higher in patients diagnosed with biliary cystadenoma (n = 22) as compared to patients diagnosed with simple hepatic cysts (n = 8).…”

Intrahepatic biliary cystadenoma—diagnosis and treatment options

“…Diagnosis and differential diagnosis of cystadenomas and cystadenocarcinomas are rather challenging (8). On USG images, they often appear as cystic formations, which are further examined with the aid of CT and MRI, often using hepatotropic X-ray contrast media.…”