Wachstumsschmerzen

Adolf, Stefanie; Braun, Sepp; Meurer, Andrea

doi:10.1007/s00132-019-03745-2

Cited by 2 publications

(4 citation statements)

References 24 publications

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“…Commonly, pediatricians see children complaining of in the legs, without any abnormality in the physical examination. 6,13,15 Often, a thorough investigation is performed even if lower limb pain does not point to serious underlying conditions such as malignancies, osteomyelitis, vaso-occlusive episodes, or sickle cell disease. 15,24,25 If exams are normal, the child is diagnosed as having GP, despite the fact that growth is a non-painful event and the lower limb pain is not associated with the specific sensitivity of the bone growth plate.…”

Section: Discussionmentioning

confidence: 99%

“…6,13,15 Often, a thorough investigation is performed even if lower limb pain does not point to serious underlying conditions such as malignancies, osteomyelitis, vaso-occlusive episodes, or sickle cell disease. 15,24,25 If exams are normal, the child is diagnosed as having GP, despite the fact that growth is a non-painful event and the lower limb pain is not associated with the specific sensitivity of the bone growth plate. 1 This diagnosis may be incorrect, as lower limb pain may reflect as a precursor/comorbidity with migraine; however, it is useful to reassure the child's parents, who are informed that the GP have a benign and self-limiting course.…”

Section: Discussionmentioning

confidence: 99%

“…Commonly, pediatricians see children complaining of pain in the legs, without any abnormality in the physical examination 6,13,15 . Often, a thorough investigation is performed even if lower limb pain does not point to serious underlying conditions such as malignancies, osteomyelitis, vaso‐occlusive episodes, or sickle cell disease 15,24,25 .…”

Section: Discussionmentioning

confidence: 99%

“…The exact pathophysiological mechanism that produces GP is not known, 5,15 but there is a similarity with migraine due to the sudden onset, severity, and recurrence of attacks, 11,16,17 suggesting a common pathogenesis 17 . They can represent a non‐inflammatory pain amplification syndrome in early childhood, with lower pain thresholds 13,18 .…”

Section: Introductionmentioning

confidence: 99%

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“Growing pains” in children and adolescents as an early symptom of migraine: A prospective study

Silva‐Néto,

Soares,

Souza

et al. 2023

Headache

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BackgroundChildren and adolescents may experience pain in the lower limbs, predominantly at the end of the day or during the night, without any relation to organic disease. These pains are often called “growing pains” (GP) by pediatricians and orthopedists. They are commonly attributed to rapid growth.ObjectiveThe aim of this study was to review and characterize GP in children and adolescents as a precursor/comorbidity with migraine.MethodsThe study was of a cross‐sectional, prospective, longitudinal cohort, with group comparison. A sample of 100 children/adolescents born to mothers with migraine seen at a headache clinic was recruited in a random order chosen by lot, maintaining the ratio of 1:1 for the group with GP and the controls. Both groups were followed for a period of 5 years.ResultsAfter 5 years of follow‐up, 78 patients completed the study, of which 42 were from the GP group and 36 were from the control group. Headache fulfilling the International Classification of Headache Disorders, 3rd edition diagnostic criteria for migraine without aura or probable migraine occurred in 32/42 (76%) of patients with GP and in 8/36 (22%) of controls (p < 0.001). In the sample that initially had “growing pains,” these pains persisted in 6/42 (14%) and appeared in 14/36 (39%) of those who were previously asymptomatic (p = 0.026).ConclusionsPain in the lower limbs of children and adolescents, commonly referred to as GP by pediatricians and orthopedists, may reflect a precursor or comorbidity with migraine.

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