War victims in need of physical rehabilitation in Croatia

Henigsberg, Neven; Lagerkvist, Bengt; Matek, Zrinjka; Kostović, Ivica

doi:10.1177/140349489702500309

Cited by 8 publications

(3 citation statements)

References 8 publications

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“…A large need for rehabilitation of Croatian war casualties was described in a number of manuscripts in medical literature [3][4][5][6]. Those unfortunate circumstances were a significant reason for the increased development and understanding of real value of rehabilitation medicine and also for an objective analysis of limitations in contemporary rehabilitation medicine in Croatia [3,4].…”

Section: Introductionmentioning

confidence: 99%

Physical and rehabilitation medicine training center in Split, Croatia: striving to achieve excellence in education of a rehabilitation team

Vlak

Šošo

Poljičanin

et al. 2013

Disability and Rehabilitation

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Academic setting such as PRM training center Split enables education for different health professionals at the same place and time, which provides opportunities for learning about competencies of other team members and development of future collaboration. Also, a uniform approach to education in rehabilitation medicine is provided for all health professionals. All of this sets a solid foundation for education of integrated rehabilitation team and achieving excellence in contemporary Croatian PRM. Implications for Rehabilitation In order to achieve high quality rehabilitation it is necessary to make education accessible to all rehabilitation team members. Implementation of rehabilitation principles in undergraduate education sets a good foundation for the development of postgraduate and specialty training in rehabilitation medicine. Academic setting such as physical and rehabilitation medicine training center Split provides a uniform approach to education in rehabilitation medicine for all health professionals.

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Section: Introductionmentioning

confidence: 99%

Physical and rehabilitation medicine training center in Split, Croatia: striving to achieve excellence in education of a rehabilitation team

Vlak

Šošo

Poljičanin

et al. 2013

Disability and Rehabilitation

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“…Indeed, the impact of SCI can range from complete or partial paralysis of the body below the lesion site, to sometimes partial or complete recovery [1,2]. The incidence of SCI in the world ranges between 10.4 and 83 cases per million people per year, depending on the region analyzed [8][9][10]. However, in world regions affected by war, the incidence of SCI transiently multiplies [10].…”

Section: Introductionmentioning

confidence: 99%

“…The incidence of SCI in the world ranges between 10.4 and 83 cases per million people per year, depending on the region analyzed [8][9][10]. However, in world regions affected by war, the incidence of SCI transiently multiplies [10]. Furthermore, care for people affected by SCI is predominantly given at home, the cost of which can run into millions of dollars and is a great strain on the patient and the caregiver.…”

Section: Introductionmentioning

confidence: 99%

Acute adaptive responses of central sensorimotor neurons after spinal cord injury

Thompson

DiBona

Dubey

et al. 2010

Translational Neuroscience

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Spinal cord injury (SCI) can be a lifelong, devastating condition for both the patient and the caregiver, with a daunting incidence rate. Still, there are only limited available therapies and the effectiveness of precise regeneration within the central nervous system is minimal throughout postnatal life. Recently, improved regeneration after SCI was seen by manipulating a pathway in sensorimotor neocortices that is involved in phosphorylation of an RNA binding protein (RBP) required for mRNA translation, the Eukaryotic translation initiation factor 4E (eIF4E). Our data identifies rapid molecular alterations of eIF4E in the sensorimotor neocortices 1 and 3 days after a lateral hemisection SCI, used as a model for Brown-Séquard syndrome. The function of an RBP depends on both its distribution sites within the cell and its phosphorylation states. Indeed, we found both to be affected after SCI. There was a distinct subcellular redistribution of eIF4E and phosphorylated-eIF4E was reduced, indicating that the eIF4E's translation was disrupted. Upon identification and analysis of the mRNA cargo of eIF4E in uninjured sensorimotor neocortices, we found that eIF4E binds both Importin-13 (Ipo13) and Parvalbumin (Pv) mRNAs, indicating a role in their translation. Remarkably, eIF4E's interaction with both Ipo13 and Pv mRNAs was disrupted 1 and 3 days after SCI, despite preservation of total Ipo13 and Pv mRNA levels. Finally, we detected a selective loss of expression of both IPO13 and PV proteins in projection neurons of sensorimotor neocortices, as well as their disrupted dendritic polarity. Since IPO13 is predominantly expressed in neocortical projection neurons and PV in a subset of neocortical interneurons, these data suggest a strong acute effect of SCI on neocortical microcircuitry. Taken together, these data indicate that neocortical eIF4E and a subset of mRNAs may be rapidly recruited to translational machinery after SCI to promote adaptive regeneration response of sensorimotor neurons.

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Rehabilitation Psychology

Stiers

Perry

Kennedy

et al. 2011

IAAP Handbook of Applied Psychology

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A growing interest in cognition in aging has been observed because of both the epidemiologic factor of an increase in the lifespan of the world's population and the cognitive changes behaviorally and biologically detectable in this population. The most complex of language components and fundamental in social interaction, discourse production and comprehension are among the most scarcely explored cognitive functions in this context. This review presents and discusses discourse processing in healthy aging with regard to theoretical, behavioral, and neuroimaging evidence. Cognitive and neurobiological models are reviewed, such as the Hemispheric Asymmetry Reduction in Older Adults (HAROLD) model and the Posterior-Anterior Shift in Aging (PASA) model. Among the neuropsycholinguistic research developed to characterize discourse processing in aging individuals, which has contributed to the prevention and treatment of language impairment and the maintenance of communicative competence in aging, studies on the relationship between discourse and working memory, attention, and some executive components are discussed. Regarding neuroimaging data, very few studies that have included cognitive tasks and discourse stimuli were found. Such studies suggest that discourse processing requires not only the participation of both brain hemispheres, but also a more prominent activation of frontal regions. Considering the great complexity and usefulness of discourse in elderly adults' daily communication and the emergence of cognitive defi cits related to aging in complex information processing, the necessity of further behavioral and neuroimaging studies, including discourse processing tasks, comparing tasks involving executive, attentional, and mnemonic demands becomes evident.

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War victims in need of physical rehabilitation in Croatia

Cited by 8 publications

References 8 publications

Physical and rehabilitation medicine training center in Split, Croatia: striving to achieve excellence in education of a rehabilitation team

Physical and rehabilitation medicine training center in Split, Croatia: striving to achieve excellence in education of a rehabilitation team

Acute adaptive responses of central sensorimotor neurons after spinal cord injury

Rehabilitation Psychology

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