Warfarin-Induced Spontaneous Bilateral Breast and Extrathoracic Hematoma in an Elderly Woman

Abstract

Warfarin- induced spontaneous breast hematoma is a very rare disease, with only a few cases having been reported in the literature so far. We describe an 80-year-old woman who had warfarin therapy due to deep vein thrombosis in a lower extremity. The patient was admitted with a history of swelling and red area on her bilateral breasts, chest wall, right arm, and right flank. She was treated conservatively with success. She was discharged after about 3 weeks without complications and was well at 6 months’ follow-up.

Spontaneous massive pectoral hematoma induced by vitamin K antagonist therapy: a case report

“…It includes a cessation of anticoagulation, blood transfusion as needed, and the administration of vitamin K, FFP, and even the prothrombin complex concentrate, in order to reverse the effect of VKA therapy. If the patient is hemodynamically stable, conservative treatment is preferable, with close monitoring of vitals, hemoglobin, and INR [ 8 ]. In cases of no improvement after conservative treatment, or when the patient is in hemorrhagic shock, due to uncontrolled bleeding, invasive treatment is indicated, which can be an open surgery or transcatheter arterial embolization [ 5 , 9 - 10 ].…”