Wastewater surveillance forSalmonellaTyphi and its association with seroincidence of enteric fever in Vellore, India
Dilip Abraham,
Lalithambigai Kathiresan,
Midhun Sasikumar
et al.
Abstract:Background Blood culture based surveillance for typhoid fever has limited sensitivity, encountering operational challenges in resource-limited settings. Environmental surveillance targeting Salmonella Typhi (S. Typhi) shed in wastewater (WW), coupled with cross-sectional serosurveys of S. Typhi specific antibodies estimating exposure to infection, emerges as a promising alternative. Methods We assessed the feasibility and effectiveness of wastewater (WW) and sero-surveillance for S. Typhi in Vellore, India, fr… Show more
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