Water-based polyurethane 3D printed scaffolds with controlled release function for customized cartilage tissue engineering

Hung, Kun‐Che; Tseng, Ching-Shiow; Dai, Lien-Guo; Hsu, Shan‐hui

doi:10.1016/j.biomaterials.2016.01.019

Cited by 224 publications

(142 citation statements)

References 55 publications

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“…Many different techniques have been developed in the recent years to build cell culture platforms and scaffolds for tissue engineering, including selective laser sintering, stereo lithography, fused filament fabrication, microfabrication, phase separation, electrospinning and 3D printing . Electro‐hydrodynamic jet (E‐jet) printing is a new high‐resolution printing method whereby the geometric feature of the built scaffolds can be precisely controlled using a broad range of materials .…”

Section: Introductionmentioning

confidence: 99%

“…6,7,15 Many different techniques have been developed in the recent years to build cell culture platforms and scaffolds for tissue engineering, including selective laser sintering, 16 stereo lithography, 17 fused filament fabrication, 18 microfabrication, 11 phase separation, 19 electrospinning 20 and 3D printing. [21][22][23][24] Electro-hydrodynamic jet (E-jet) printing is a new high-resolution printing method whereby the geometric feature of the built scaffolds can be precisely controlled using a broad range of materials. 25,26 E-jet printing is a nano-manufacturing process, whereby the printing materials, such as polymer solutions or polymer melt, are induced using an electric field to form a fine jet much smaller than the nozzle diameter, overcoming the limitations imposed by nozzle size, thus producing micro-to nano-scale features.…”

Section: Introductionmentioning

confidence: 99%

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Control of cell growth on 3D‐printed cell culture platforms for tissue engineering

Tan

Liu

Zhong

et al. 2017

J Biomedical Materials Res

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Biocompatible tissue growth has excellent prospects for tissue engineering. These tissues are built over scaffolds, which can influence aspects such as cell adhesion, proliferation rate, morphology, and differentiation. However, the ideal 3D biological structure has not been developed yet. Here, we applied the electro-hydrodynamic jet (E-jet) 3D printing technology using poly-(lactic-co-glycolic acid, PLGA) solution to print varied culture platforms for engineered tissue structures. The effects of different parameters (electrical voltage, plotting speed, and needle sizes) on the outcome were investigated. We compared the biological compatibility of the 3D printed culture platforms with that of random fibers. Finally, we used the 3D-printed PLGA platforms to culture fibroblasts, the main cellular components of loose connective tissue. The results show that the E-jet printed platforms could guide and improve cell growth. These highly aligned fibers were able to support cellular alignment and proliferation. Cell angle was consistent with the direction of the fibers, and cells cultured on these fibers showed a much faster migration, potentially enhancing wound healing performance. Thus, the potential of this technology for 3D biological printing is large. This process can be used to grow biological scaffolds for the engineering of tissues. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 3281-3292, 2017.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Control of cell growth on 3D‐printed cell culture platforms for tissue engineering

Tan

Liu

Zhong

et al. 2017

J Biomedical Materials Res

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“…Another natural polymer, hyaluronic acid (HA), has been evaluated for bioprinting, but, it suffers from poor mechanical properties. Hence, it has been used in bioprinting as viscosity enhancer in combination with other polymers …”

Section: Bone Biofabrication Parameters and Requirementsmentioning

confidence: 99%

Advancing Frontiers in Bone Bioprinting

Ashammakhi

Hasan

Kaarela

et al. 2019

Adv Healthcare Materials

189

182

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Three‐dimensional (3D) bioprinting of cell‐laden biomaterials is used to fabricate constructs that can mimic the structure of native tissues. The main techniques used for 3D bioprinting include microextrusion, inkjet, and laser‐assisted bioprinting. Bioinks used for bone bioprinting include hydrogels loaded with bioactive ceramics, cells, and growth factors. In this review, a critical overview of the recent literature on various types of bioinks used for bone bioprinting is presented. Major challenges, such as the vascularity, clinically relevant size, and mechanical properties of 3D printed structures, that need to be addressed to successfully use the technology in clinical settings, are discussed. Emerging approaches to solve these problems are reviewed, and future strategies to design customized 3D printed structures are proposed.

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“…Some advanced techniques such as electrospinning [154,155], rapid prototyping [156,157] including different methods of 3D printing and 3D plotting have also been developed [158][159][160][161][162].…”

Section: Fabrication Of Porous Biopusmentioning

confidence: 99%