Based on velocity and nutrient data from satellite and in situ measurements, we studied the temporal and spatial variations for 22‐year (1993–2014) cross‐shelf nutrient exchange at the 200‐m isobath section in the East China Sea. Since nitrate and phosphate concentrations were highly correlated (correlation coefficient of 0.95), only nitrate transport was investigated in detail. The cross‐shelf nutrient exchange is explored from whole to detail. The results show that the 22‐year averaged section‐integrated nitrate transport (FQ) is 22.0 ± 12.4 kmol/s (+ in the on‐shelf direction). Its interannual variation is larger than its seasonal variation, but no persistent interannual signal exists. The on‐ and off‐shelf components of FQ are about twice as large as FQ itself, and the temporal variation of FQ is mainly determined by its on‐shelf component. The depth‐integrated nitrate transport (Fq) along the 200‐m isobath shows that the largest on‐ and off‐shelf nitrate transports occur northeast of Taiwan, whereas the on‐shelf nitrate transport at the middle East China Sea is also important. Moreover, the on‐shelf component of Fq northeast of Taiwan mainly determines the temporal variation in FQ. The mean and standard deviation of the sectional nitrate flux (F) suggest that the largest variation in F occurs northeast of Taiwan, 150 m below the surface. Combining results from empirical orthogonal function analysis, the horizontal and vertical structures of F are determined by velocity and nitrate concentration, respectively, whereas the temporal variation of F is mainly determined by velocity and the geostrophic component.