“…Mexico have established 25 µg/L, and Bangladesh 5 µg/L (Chowdhury et al, 2000;NOM-127-SSA1-1994;Khalequzzaman et al, 2005). Cancers connected with As in water have been associated with cellular, molecular, and genetic modifications such as repression of DNA repair genes, alteration in gene expression and methylation, micronucleus formation, chromosomal aberrations, polymorphisms, genotoxicity, cytotoxicity, telomere shortening, decreased DNA damage response (DDR), and DNA damage (Murray and Sharmin, 2015;Shibata et al, 2016;Akter et al, 2016). The principal factors regulating DNA damage are diet, alcohol consumption, age, smoking, exercise, and exposure to environmental toxins such as asbestos, heavy metals, radiation (ultraviolet (UV) light, gamma rays), and stress (Gidron et al, 2006).…”