Water-soluble Cobalt(II) &amp; Cobalt(III) complexes supported by new triazine Schiff base ligands: Synthesis, structure and biological evaluation

Parveen, S.; Velmurugan, Gunasekaran; Sinn, Ekkehard; Venuvanalingam, Ponnambalam; Sundararajan, G.

doi:10.1016/j.jphotobiol.2018.10.008

Cited by 30 publications

(15 citation statements)

References 63 publications

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“…[ 1–3 ] On the other hand, Schiff base compounds attract considerable research due to their pharmacological activity and the tendency toward the formation of complexes with almost all the transition metals. [ 4,5 ] These metal complexes of Schiff bases possess high inspect in medicinal chemistry, such as antiviral, anticancer, antibacterial, antifungal, antioxidant anticonvulsant, and anti‐inflammatory activities. [ 6,7 ] It was reported that Schiff base compounds formed from amine of carbohydrazide with heterocyclic aldehyde are more stable and have high abilities to coordinate with the transition metal ions.…”

Section: Introductionmentioning

confidence: 99%

New heterocyclic Schiff base‐metal complex: Synthesis, characterization, density functional theory study, and antimicrobial evaluation

Hashem

Mohamed

Farag

et al. 2021

Applied Organom Chemis

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A new series of heterocyclic Schiff base complexes derived from the condensation of nicotinohydrazide with different heterocyclic aldehyde, followed by metalation with Co (II) and Cu (II) metal ions. The chemical structures of the synthesized compounds have been characterized by elemental analysis, Fourier transform infrared spectroscopy, proton nuclear magnetic resonance, ultraviolet–visible spectroscopy, and magnetic susceptibility. The spectral and magnetic data confirmed their chemical structures, furthermore, the geometry of Cu (II) and Co (II) complexes were square‐planar or distorted tetrahedral. X‐ray diffraction measurements supported the crystalline structures of the metal complexes rather than the amorphous form of the parent Schiff bases. Thermogravimetric analysis revealed the upgrading of the thermal stability of metal complexes compared to their Schiff base ligands. Antimicrobial efficacies of the Schiff base ligands and their corresponded metal complexes were screened against Staphylococcus aureus and Bacillus subtilis as Gram‐positive bacteria, Escherichia coli, and Proteus vulgaris as Gram‐negative bacteria, and fungi Aspergillus flavus, Candida albicans. The antimicrobial inhibitory data revealed higher antimicrobial activities of metal complexes compared to their Schiff base ligands. Density functional theory module by Gaussian 09 W software proved the chemical reactivity of the prepared Schiff base ligands based on the total energy, energy gap, EHOMO, and ELUMO energies.

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Section: Introductionmentioning

confidence: 99%

New heterocyclic Schiff base‐metal complex: Synthesis, characterization, density functional theory study, and antimicrobial evaluation

Hashem

Mohamed

Farag

et al. 2021

Applied Organom Chemis

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“…34 In the cobalt complex, the shoulder at 482 nm was assigned to a 4 T 1g (F) -4 T 1g (P) spin allowing for a d-d transition of the octahedral geometry. 26,35,36 1 H NMR and mass characterisation…”

Section: Uv-vis Absorption Spectroscopymentioning

confidence: 99%

“…The comparatively larger K value indicated a strong interaction between the trinuclear cobalt complex and BSA that was comparable to K values obtained for other Co-containing compounds (6.08 Â 10 4 M À1 and 1.01 Â 10 5 M À1 ). 26 Synchronous fluorescence methods were used to obtain a better understanding of the binding interaction in the BSA microenvironment after the addition of the tested compounds. According to Miller,49 the variance between the emission and excitation wavelengths in fluorescence spectroscopy reveals the type of chromophore in the protein moiety.…”

Section: Njc Papermentioning

confidence: 99%

A trinuclear cobalt coordination complex constructed using novel triazine ligandsviaone-pot green synthesis: structural properties and biological evaluation

et al. 2023

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“…Free radical scavenging activity and reducing capacities of newly synthesized compounds were confirmed by FRAP and phosphomolybdenum assay. The salts exhibit good antioxidant property is due to the presence of nitrogen content [13].…”

Section: Antioxidant Studiesmentioning

confidence: 99%

Synthesis, Thermal Reactivity, and Antioxidant Studies of Aminoguanidinium Salts of Aspartic and Glutamic Acids

Parveen¹,

Manikandan²,

Govindarajan

et al. 2020

Asian J Pharm Clin Res

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Objective: Our main scope and objectives are to prepare aminoguanidinium salts of amino acids and to characterize them using analytical, IR, and thermal studies, to study the mode of thermal decomposition of aminoguanidinium salts, and to characterize the antioxidants behavior of aminoguanidinium salts. Methods: Elemental analysis for C, H, and N was performed on a Vario ELIII elemental analyzer. The IR spectra were recorded on a JASCO-4100 spectrophotometer as KBr pellets in the range of 400–4000 cm-1. The simultaneous TG-DTA studies were under taken on a PerkinElmer SII thermal analyzer and the curves obtained in air using platinum cups as holders with ~ 3 mg of the samples at the heating rate of 10°C/min. The antioxidant capacities of different salts were estimated according to the literature procedure. Results: Aspartic acid forms bis-aminoguanidinium salt, whereas glutamic acid forms both mono- and bis-aminogunidinium salts. The IR spectral data of the aminogunidinium salts of aforesaid acids show N-N stretching frequencies in the region 1110–1202 cm-1 revealing the presence of aminoguanidinium moiety. Conclusion: The antioxidant properties of these salts were studied using ferric reducing antioxidant power and phosphomolybdenum assay. Results showed significant ferric reducing power which indicated the hydrogen-donating ability of the extract.

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Water-soluble Cobalt(II) & Cobalt(III) complexes supported by new triazine Schiff base ligands: Synthesis, structure and biological evaluation

Cited by 30 publications

References 63 publications

New heterocyclic Schiff base‐metal complex: Synthesis, characterization, density functional theory study, and antimicrobial evaluation

New heterocyclic Schiff base‐metal complex: Synthesis, characterization, density functional theory study, and antimicrobial evaluation

A trinuclear cobalt coordination complex constructed using novel triazine ligandsviaone-pot green synthesis: structural properties and biological evaluation

Synthesis, Thermal Reactivity, and Antioxidant Studies of Aminoguanidinium Salts of Aspartic and Glutamic Acids

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