Water-soluble oligofluorenes bearing N₁-alkylcytosine side chains as turn-on and turn-off materials in telomere DNA length sensing

Abstract

Water-soluble cationic and anionic oligofluorenes bearing N1-alkylcytosine side chains, namely, OF-1 and OF-2 were synthesized. The photoluminescence (PL) intensity of an aqueous solution of OF-1 decreased by the addition of...

Water‐soluble π‐conjugated polyfluorene bearing 6‐N1‐hexylcytosine and 6‐trimethylammoniumhexyl side chains: Synthesis, chemical properties, and sensing ability for nucleoside and telomere DNA

“…Figure 2A shows the UV–vis spectra of monomer‐1 and polymer‐1 in DMSO. A longer wavelength was observed for the absorption maximum (λ max ) of polymer‐1 (λ max = 389 nm) than for those of monomer‐1 (λ max = 282 nm) and OF‐1 (λ max = 358 nm), 23 implying that the polymer possessed a larger π‐conjugated system. From the onset wavelength (λ onset = 432 nm), the optical band gap of polymer‐1 was estimated to be E g opt = 2.9 eV.…”

“…We reported the synthesis of an oligo(fluorene), OF‐1, bearing 6‐ N 1 ‐cytosinehexyl and 6‐trimethylammoniumhexyl bromide side chains and its utility in telomere DNA sensing 23 . Cytosine group of OF‐1 interacted with nucleosides and telomere DNA.…”

Fluorescence turn‐off and turn‐on sensors of Zn2+ based on π‐conjugated poly(aryleneethynylene)s comprising alloxazine‐6,9‐diyl and 2,7‐diethynylene‐9,9‐dialkylfluorene units

“…Photoinduced electron transfer (PET) from polymer‐2 (donor) to the polymer complex (acceptor) is likely to quench the PL of polymer‐2 because the exciton could not transition to the HOMO of the acceptor. The PL quenching of π‐conjugated polymers and oligomers based on PET has been reported 38,39 …”

“…The PL quenching of π-conjugated polymers and oligomers based on PET has been reported. 38,39 Polymers 1 and 2 are likely to aggregate via interchain complexation with an excess amount of Zn 2+ . To investigate whether polymer-2 aggregated in solution upon the addition of excess Zn(OAc) 2 , the τ values of the polymer in the presence of various amounts of metal salt were measured.…”

Synthesis and optical properties of π‐conjugated polymers and oligomers bearing hexaphenylbenzene and tetraphenyl ethene units

“…CPs and COs reportedly consist of a rigid main chain with long alkyl side chains that often self-assemble into ordered structures in mixtures of good and poor solvents. [15][16][17] The ordered structures of the CPs and COs influence their fluorescence properties, forming excimerlike adducts. Therefore, the CPs that consist of a rigid main chain with HPB or TPE units, long alkyl side chains, and spacing groups to improve the planarity of the backbone structure are expected to be suitable for elucidation of the structure-ACQ and structure-AIEE relationships.…”