Water structure of poly(2-methoxyethyl acrylate) observed by nuclear magnetic resonance spectroscopy

Mochizuki, Akira; Miwa, Yuko; Yahata, Chie; Ono, Dai; Oda, Yoshinobu; Kawaguchi, Tsubasa

doi:10.1080/09205063.2020.1738042

Cited by 6 publications

(2 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, these studies were mostly conducted at temperatures below 0 °C. ,,,,,, PMEA being water-insoluble at room temperature, the evolution of its hydration with temperature above 0 °C has seldom been studied. Mochizuki et al performed a 2 D NMR study revealing that PMEA still contains about 10 wt % water between 15 and 45 °C and that water is heterogeneously distributed within the polymer. Hou and Wu prepared statistical copolymers consisting of 90 mol % MEA and 10 mol % oligo (ethylene glycol)acrylate (OEGA 480 containing eight to nine ethylene oxide units per monomer) and observed a progressive, rather than abrupt, decrease of the hydration of the copolymer with increasing temperature.…”

Section: Resultsmentioning

confidence: 99%

“…Still, PMEA is significantly hydrated (∼10 wt %) at room temperature. , Contrary to the better known PNIPAM, which dehydrates abruptly at its LCST, PMEA dehydrates progressively with increasing temperature, making it potentially suitable to design thermoresponsive hydrogels exhibiting a gradual increase of their exchange time with T . Chemical gels, homopolymers, or block copolymers containing PMEA , have been widely studied, especially in view of the strong blood compatibility ,,− of this polymer, which is attributed to its strong interaction with water, ,,− or for the design of self-assembled particles by polymerization-induced self-assembly. , However, to the best of our knowledge, PMEA has so far not been used as B block in view of preparing transient networks exhibiting thermothickening properties.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Thermosensitive Hydrogels of BAB Triblock Copolymers Exhibiting Gradually Slower Exchange Dynamics and an Unexpected Critical Reorganization Temperature Upon Heating

et al. 2022

View full text Add to dashboard Cite

BAB amphiphilic triblock copolymers comprising poly(methoxyethyl acrylate) (PMEA) B blocks of variable degrees of polymerization (x = 50, 100, or 200) and a central poly(dimethyl acrylamide) (PDMAc) hydrophilic A block with a degree of polymerization y = 400 were synthesized by reversible addition fragmentation chain transfer polymerization, and their self-assembly in water was studied by light scattering and rheology. The BAB triblocks form a transient network in aqueous solution consisting of hydrophobic B cores bridged by hydrophilic A blocks. The exchange of B blocks is fast at low temperature (10 °C) and/or low x values because PMEA is not too hydrophobic. However, the PMEA blocks become more hydrophobic with increasing temperature, leading to a decrease of the exchange rate of the B blocks and to tunable thermo-thickening properties, opposite to the classical Arrhenius behavior. In contrast to many thermosensitive BAB triblocks that undergo an abrupt sol–gel transition above the critical solubility temperature of the B blocks, the hydrophobicity of PMEA gradually increases with T, leading to a progressive increase of the viscosity of the polymer dispersion. In addition, an unprecedented reorganization of the network was observed by rheology at a critical temperature, leading to a further decrease of the exchange rate of the B blocks that is not fully reversible. These features were attributed to the progressive variation of the hydrophobic character and hydration of PMEA with temperature.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Thermosensitive Hydrogels of BAB Triblock Copolymers Exhibiting Gradually Slower Exchange Dynamics and an Unexpected Critical Reorganization Temperature Upon Heating

et al. 2022

View full text Add to dashboard Cite

show abstract

Water: The soul of hydrogels

Yuan,

Zhang,

Lin

et al. 2025

Progress in Materials Science

View full text Add to dashboard Cite

Water as the often neglected medium at the interface between materials and biology

Dargaville

Hutmacher

2022

Nat Commun

View full text Add to dashboard Cite

Despite its apparent simplicity, water behaves in a complex manner and is fundamental in controlling many physical, chemical and biological processes. The molecular mechanisms underlying interaction of water with materials, particularly polymer networks such as hydrogels, have received much attention in the research community. Despite this, a large gulf still exists in applying what is known to rationalize how the molecular organization of water on and within these materials impacts biological processes. In this perspective, we outline the importance of water in biomaterials science as a whole and give indications for future research directions towards emergence of a complete picture of water, materials and biology.

show abstract

Water structure of poly(2-methoxyethyl acrylate) observed by nuclear magnetic resonance spectroscopy

Cited by 6 publications

References 26 publications

Thermosensitive Hydrogels of BAB Triblock Copolymers Exhibiting Gradually Slower Exchange Dynamics and an Unexpected Critical Reorganization Temperature Upon Heating

Thermosensitive Hydrogels of BAB Triblock Copolymers Exhibiting Gradually Slower Exchange Dynamics and an Unexpected Critical Reorganization Temperature Upon Heating

Water: The soul of hydrogels

Water as the often neglected medium at the interface between materials and biology

Contact Info

Product

Resources

About