A method of determining friction velocity u* by measurement in a wind-wave tunnel is proposed, based on the similarity law of the turbulent boundary layer. The method is based essentially on the application of a two-layer model to the velocity defect profile a logarithmic velocity distribution is applied to the inner boundary layer and Hama's profile, F=9.6(1-0)2, to the outer layer, where F is the non-dimensional velocity defect function, 7 the non-dimensional height.This method can determine friction velocity u* within a few percent of uncertainty, and has higher accuracy than the logarithmic method generally used, in some case of wind-wave tunnel experiments. The method works with precision if used in the early stage of development of the turbulent boundary layer, but not if used in the later stage, when the turbulent boundary layer has fully developed and the whole air flow in the wind-wave tunnel becomes turbulent.