Waterjet dissection of the vestibulocochlear nerve: an experimental study

Tschan, Christoph A.; Gaab, M. R.; Krauss, Joachim K.; Oertel, Joachim

doi:10.3171/2008.5.17561

Cited by 19 publications

(13 citation statements)

References 53 publications

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“…7 In another study, the vestibulocochlear nerve in rats was preserved up to 8 bar without functional deficit in the outcome. 6 This studies suggest that a pressure level of up to 8 bar is safe for brain tissue dissection preserving vessels and cranial nerves.…”

Section: Discussionmentioning

confidence: 80%

New applicator improves waterjet dissection quality

Tschan

Krauss

et al. 2010

British Journal of Neurosurgery

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Section: Discussionmentioning

confidence: 80%

New applicator improves waterjet dissection quality

Tschan

Krauss

et al. 2010

British Journal of Neurosurgery

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“…Jet pressures of 10 bar resulted in complete functional and-although the nerve's continuity was preserved-severe structural lesion. No recovery was found after 12 weeks [ 46 ].…”

Section: Introductionmentioning

confidence: 89%

Animal Models for Experimental Neurosurgery of Peripheral and Cranial Nerves

Oertel

Tschan²,

Keiner

2016

Neuromethods

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Common experimental models for investigation of cranial and peripheral nerve function after trauma include sciatic nerve crush injuries and direct cutting of cochlear or facial nerves. Partial nerve transection, spinal nerve ligation, and chronic constriction injury are applied in neuropathic pain studies. Although these models are well established due to their potential to create reliable and reproducible results, an experimental setup for studying incomplete nerve lesions which resemble the intraoperative surgical condition was missing for years.In neurosurgery, manipulation of peripheral or cranial nerves-such as in surgical procedures in the cerebellar-pontine angle or at the skull base-may lead to severe functional loss despite morphologically intact nerves. In the past years, different therapeutic agents for regeneration of the functional recovery have been investigated intensely. The authors' group has developed animal models to investigate the therapeutic potential of various substances in incomplete nerve injuries. In these models, the severity of the nerve lesion with distinct functional loss and recovery depends on the preset jet pressures.

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“…Moreover, precise tissue dissection together with preservation of vessels and nerves can be achieved. 10,11 Conventional pressure-driven continuous water jet technology has already been applied for endoscopic treatment. 12 However, its use was limited to transmucosal injection of water into the submucosal layer to elevate the mucosa in preparation for EMR rather than for tissue dissection, 13,14 probably due to the continuous nature of the water jet.…”

Section: E Ndoscopic Submucosal Dissection (Esd)mentioning

confidence: 99%

“…Water jet technology, based on conventional pressure‐driven continuous jet or laser/electrically induced pulsed pressure, provides an alternative method for dissecting soft tissues without damaging small vessels or causing mechanical and thermal damage. Moreover, precise tissue dissection together with preservation of vessels and nerves can be achieved . Conventional pressure‐driven continuous water jet technology has already been applied for endoscopic treatment .…”

Section: Introductionmentioning

confidence: 99%