3D dynamic interaction of two adjacent elastic foundations embedded in a finite layered soil region rested in a homogeneous elastic isotropic half-space with a transient dynamic source is studied. The hybrid computational model, the corresponding numerical scheme and the accompanied software are developed, verified and inserted in detail parametric study. The hybrid approach is based on (a) finite element method (FEM) describing the scattered wave field in a finite layered soil profile with two foundations; (b) boundary element method (BEM) considering waves radiating from a dynamic transient source in elastic semiinfinite range. The aim is to propose an efficient hybrid methodology for evaluation of the dynamic response of a foundation-soil-foundation system, taking into account (a) the whole wave path from the dynamic source, through the layered soil region, till the underground structures; (b) the damage state of the geological material. The BEM model is based on the 3D elastodynamic fundamental solution in Fourier domain and it is applied in order to obtain frequency-dependent stiffness matrix and load vector of the dynamically active semi-infinite geological zone. Once the BEM model is formulated, it is inserted as a macro-finite element in the FEM software package ABAQUS. The frequency-dependent FEM model describing the wave field in finite layered soil profile with two elastic foundations is realized by ABAQUS. Solutions in time domain are obtained through application of the inverse fast Fourier transform. As a final result an efficient hybrid model comprising all in one: dynamic (seismic or other type) source-homogeneous elastic half-space-finite heterogeneous by layers and foundations soil profile, is presented. Parametric study illustrating the sensitivity of the dynamic field to key factors such as the type and properties of the load, the soil layering, the material properties of the far-and near-field soil regions, the damaged state of the geological material and the foundation-soil-foundation interaction is shown and discussed.