Wavefront-Optimized Ablation Versus Topography-Guided Customized Ablation in Myopic LASIK: Comparative Study of Higher Order Aberrations

awady, Hatem E. El; Ghanem, Asaad A.; Saleh, Sameh

doi:10.3928/15428877-20110421-01

Cited by 58 publications

(52 citation statements)

References 20 publications

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“…LASIK outcomes appear to have improved in safety and efficacy with the evolutions described earlier1,13 in both refractive outcomes and induced high-order aberrations 5,14,15…”

Section: Introductionmentioning

confidence: 72%

Topography-modified refraction (TMR): adjustment of treated cylinder amount and axis to the topography versus standard clinical refraction in myopic topography-guided LASIK

Kanellopoulos¹

2016

OPTH

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PurposeTo evaluate the safety, efficacy, and contralateral eye comparison of topography-guided myopic LASIK with two different refraction treatment strategies.SettingPrivate clinical ophthalmology practice.Patients and methodsA total of 100 eyes (50 patients) in consecutive cases of myopic topography-guided LASIK procedures with the same refractive platform (FS200 femtosecond and EX500 excimer lasers) were randomized for treatment as follows: one eye with the standard clinical refraction (group A) and the contralateral eye with the topographic astigmatic power and axis (topography-modified treatment refraction; group B). All cases were evaluated pre- and post-operatively for the following parameters: refractive error, best corrected distance visual acuity (CDVA), uncorrected distance visual acuity (UDVA), topography (Placido-disk based) and tomography (Scheimpflug-image based), wavefront analysis, pupillometry, and contrast sensitivity. Follow-up visits were conducted for at least 12 months.ResultsMean refractive error was −5.5 D of myopia and −1.75 D of astigmatism. In group A versus group B, respectively, the average UDVA improved from 20/200 to 20/20 versus 20/16; post-operative CDVA was 20/20 and 20/13.5; 1 line of vision gained was 27.8% and 55.6%; and 2 lines of vision gained was 5.6% and 11.1%. In group A, 27.8% of eyes had over −0.50 diopters of residual refractive astigmatism, in comparison to 11.7% in group B (P<0.01). The residual percentages in both groups were measured with refractive astigmatism of more than −0.5 diopters.ConclusionTopography-modified refraction (TMR): topographic adjustment of the amount and axis of astigmatism treated, when different from the clinical refraction, may offer superior outcomes in topography-guided myopic LASIK. These findings may change the current clinical paradigm of the optimal subjective refraction utilized in laser vision correction.

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“…LASIK outcomes appear to have improved in safety and efficacy with the evolutions described earlier1,13 in both refractive outcomes and induced high-order aberrations 5,14,15…”

Section: Introductionmentioning

confidence: 72%

Topography-modified refraction (TMR): adjustment of treated cylinder amount and axis to the topography versus standard clinical refraction in myopic topography-guided LASIK

Kanellopoulos¹

2016

OPTH

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“…These improvements have further advanced the clinical outcomes of the LASIK procedure1,13 in correcting not just the spherocylindrical refractive error, but also the higher-order aberrations, by reducing the induced spherical aberration following myopic ablation 5,14,15…”

Section: Introductionmentioning

confidence: 99%

Long-term bladeless LASIK outcomes with the FS200 Femtosecond and EX500 Excimer Laser workstation: the Refractive Suite

Kanellopoulos¹,

Asimellis²

2013

OPTH

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“…The introduction of the 'prolate optimization function' of the MEL80 platform (Carl Zeiss Meditec, Jena, Germany) and Wavelight Allegretto (Alcon/WaveLight Laser Technologie GmbH, Erlangen, Germany), for example, brought hope that they could optimize the postoperative asphericity of the cornea [10][11][12]. Studies show these to not only be safe and efficient as conventional treatment for correcting refractive errors, but also suggest that they might better maintain corneal shape and induce smaller increases in spherical aberrations than standard ablations [13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Three different aspheric treatment algorithms of laser-assisted sub-epithelial keratectomy in patients with high myopia

Ahn

Choi²,

Kim

et al. 2012

Jpn J Ophthalmol

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Purpose To compare visual outcomes and quality in high myopia patients treated using one of three aspheric treatment algorithms based on the NIDEK Advanced Vision Excimer Laser System. Methods Sixty eyes of 60 high myopia patients ([-6 diopter) underwent topography-guided (CATz) (20 eyes), wavefront-guided (OPDCAT) (20 eyes), or topography and wavefront-guided (OPA) (20 eyes) laser-assisted subepithelial keratectomy. Visual acuity, manifest refraction spherical equivalent (MRSE), ocular and corneal higher order aberrations, corneal asphericity, point spread function (Strehl ratio) and modulation transfer function (MTF) were compared preoperatively and 1, 3 and 6 months postoperatively.Results Six months after surgery, logMAR uncorrected visual acuity was 0.02 ± 0.09 in the CATz group, 0.02 ± 0.07 in the OPDCAT group and 0.02 ± 0.08 in the OPA group, and there were no statistically significant differences (P = 0.5355). No statistical differences were found among the three groups in MRSE (P = 0.3541). Induced spherical aberrations and the change of corneal asphericity were less in the OPA group than in the others (P \ 0.0001). The MTF was slightly better in the OPA group than in the others. The Strehl ratio showed no statistically significant differences among the three groups. Conclusions All three aspheric treatment algorithms were safe and effective in correcting high myopia. Among them, the OPA algorithm maintained optical quality and physiologic cornea longer than the others.

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Wavefront-Optimized Ablation Versus Topography-Guided Customized Ablation in Myopic LASIK: Comparative Study of Higher Order Aberrations

Abstract: Both wavefront-optimized ablation and topography-guided ablation provided good refractive results, but the latter induced fewer HOAs.

Cited by 58 publications

References 20 publications

Topography-modified refraction (TMR): adjustment of treated cylinder amount and axis to the topography versus standard clinical refraction in myopic topography-guided LASIK

Topography-modified refraction (TMR): adjustment of treated cylinder amount and axis to the topography versus standard clinical refraction in myopic topography-guided LASIK

Long-term bladeless LASIK outcomes with the FS200 Femtosecond and EX500 Excimer Laser workstation: the Refractive Suite

Three different aspheric treatment algorithms of laser-assisted sub-epithelial keratectomy in patients with high myopia

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