Wavelength-Dependent Metal-Enhanced Fluorescence Biosensors via Resonance Energy Transfer Modulation

Lee, Seungah; Kang, Seong Ho

doi:10.3390/bios13030376

Cited by 10 publications

(4 citation statements)

References 102 publications

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“…In addition, the fluorescence enhancement of QDs caused by the interaction of QDs and analytes can be attributed to surface plasmon enhanced fluorescence (SPEF), which is also referred to as metal surface enhanced fluorescence (MEF) and chelate enhanced fluorescence (CHEF). MEF is defined as the fluorescence being enhanced when the distances between fluorophores and metal are within the range of 5 to 90 nm [54], while CHEF can be due to coordination of the surface functional groups with analytes [15].…”

Section: Mechanisms Of Fluorescence Sensorsmentioning

confidence: 99%

Fluorescent Quantum Dots and Its Composites for Highly Sensitive Detection of Heavy Metal Ions and Pesticide Residues: A Review

et al. 2023

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Quantum dots nanomaterials have attracted extensive interest for fluorescence chemical sensors due their attributes, such as excellent optical characteristics, quantum size effects, interface effects, etc. Moreover, the fluorescence properties of quantum dots can be adjusted by changing their structure, size, morphology, composition, doping, and surface modification. In recent years, quantum dots nanomaterials have been considered the preferred sensing materials for the detection of heavy metal ions and pesticide residues by the interactions between quantum dots and various analytes, showing excellent sensitivity, selectivity, and interference, as well as reducing the cost of equipment compared with traditional measurement methods. In this review, the applications and sensing mechanisms of semiconductor quantum dots and carbon-based quantum dots are comprehensively discussed. The application of semiconductor quantum dots, carbon quantum dots, graphene quantum dots, and their nanocomposites that are utilized as fluorescence sensors are discussed in detailed, and the properties of various quantum dots for heavy metal ion and pesticide residue determination are also presented. The recent advances in and application perspectives regarding quantum dots and their composites are also summarized.

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Section: Mechanisms Of Fluorescence Sensorsmentioning

confidence: 99%

Fluorescent Quantum Dots and Its Composites for Highly Sensitive Detection of Heavy Metal Ions and Pesticide Residues: A Review

et al. 2023

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“…Fluorescence can serve as an excellent sensing probe acting as an effective transducer for transmitting fluorescent signals in biometric events collected using various detectors. Fluorescence systems incorporating nanomaterials that translate interactions between molecular recognition elements and targets into changes in fluorescence wavelength and intensity, such as fluorescence resonance energy transfer (FRET) and metal-enhanced fluorescence (MEF) effects, have been greatly improved with the continuous development of nanomaterials 71 – 73 .…”

Section: Fluorescence Sensingmentioning

confidence: 99%

Current research status of tumor cell biomarker detection

Jiang,

Lin,

Chen

et al. 2023

Microsyst Nanoeng

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With the annual increases in the morbidity and mortality rates of tumors, the use of biomarkers for early diagnosis and real-time monitoring of tumor cells is of great importance. Biomarkers used for tumor cell detection in body fluids include circulating tumor cells, nucleic acids, protein markers, and extracellular vesicles. Among them, circulating tumor cells, circulating tumor DNA, and exosomes have high potential for the prediction, diagnosis, and prognosis of tumor diseases due to the large amount of valuable information on tumor characteristics and evolution; in addition, in situ monitoring of telomerase and miRNA in living cells has been the topic of extensive research to understand tumor development in real time. Various techniques, such as enzyme-linked immunosorbent assays, immunoblotting, and mass spectrometry, have been widely used for the detection of these markers. Among them, the detection of tumor cell markers in body fluids based on electrochemical biosensors and fluorescence signal analysis is highly preferred because of its high sensitivity, rapid detection and portable operation. Herein, we summarize recent research progress in the detection of tumor cell biomarkers in body fluids using electrochemical and fluorescence biosensors, outline the current research status of in situ fluorescence monitoring and the analysis of tumor markers in living cells, and discuss the technical challenges for their practical clinical application to provide a reference for the development of new tumor marker detection methods.

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“…[ 18 ] Other reviews that provide overviews of nanoparticle fabrication, MEF mechanisms, and incorporation in biological applications with emission wavelengths from ultra‐violet to second near infrared windows have also been reported. [ 9,12,19 ] In this manuscript, we discussed some of the most recent advances in the application of metal nanoparticles and nano‐patterns in MEF‐based fluorescent sensing. Different to previous reviews, we focused on three dimensional‐nanostructures and nano‐patterned surfaces and reviewed relevant work with an emphasis on in‐depth discussion of the effects of nanomaterial structure and size on MEF.…”

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

Advances in three dimensional metal enhanced fluorescence based biosensors using metal nanomaterial and nano‐patterned surfaces

Goodrum,

2023

Biotechnology Journal

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Metal enhanced fluorescence (MEF) is a phenomenon that increases fluorescence signal through placement of metal near a fluorophore. For biosensing applications, MEF‐based biosensors are becoming increasingly popular as it enables highly sensitive detection of molecules, important for early diagnosis. The structure and size of the metal influence the optical properties through enhancing the fluorophore photostability and light absorption and emission. In recent years, many metal nanostructures have been fabricated and examined for their effectiveness in developing MEF‐based biosensors. This review focuses on the latest applications of three‐dimensional nanostructures and nano‐patterned surfaces used to develop and improve fluorescence sensing via MEF. Current reviews mostly discussed the applications of two dimensional MEF and metal‐nanoparticles‐based MEF with a focus on fabrication of nanoparticles and metal substrates. In this article, we focused more on the effect of the metal nanostructure and size on MEF and then provided an in‐depth summary of the performance of the state‐of‐the‐art three dimensional MEF‐based biosensors. While more work is needed to demonstrate applicability for complex samples, it is evident that with the use of metal nanoparticles and three dimensional nano‐patterns, the assay sensitivity of fluorescence‐based detection can be greatly improved, making it suitable for use in early disease diagnostics.

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Wavelength-Dependent Metal-Enhanced Fluorescence Biosensors via Resonance Energy Transfer Modulation

Cited by 10 publications

References 102 publications

Fluorescent Quantum Dots and Its Composites for Highly Sensitive Detection of Heavy Metal Ions and Pesticide Residues: A Review

Fluorescent Quantum Dots and Its Composites for Highly Sensitive Detection of Heavy Metal Ions and Pesticide Residues: A Review

Current research status of tumor cell biomarker detection

Advances in three dimensional metal enhanced fluorescence based biosensors using metal nanomaterial and nano‐patterned surfaces

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