WBC reduction in cryopreserved RBC units

Arnaud, Françoise; Meryman, Harold T.

doi:10.1046/j.1537-2995.2003.00358.x

Cited by 5 publications

(10 citation statements)

References 26 publications

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“…Here we take advantage of the effective formalism provided by the Supermodel (SM; Cavaliere et al 2009, see http://people.sissa.it/∼lapi/ Supermodel/) to show that the complex ICP thermal states still allow a neat physical description of the spherically-averaged pressure profiles. In response to the intriguing challenge posed by Arnaud et al (2010), we find two basic shapes to span the observed variance in the pressure profiles for low z 0.2, and predict that they are to converge into a closely universal one for high z 0.5.…”

Section: Introductionmentioning

confidence: 78%

“…Bypassing such complexities, a 'universal' fitting formula for the pressure profiles has been proposed by Nagai et al (2007) to interpret the outcomes of hydrodynamical simulations of relaxed clusters (see also Battaglia et al 2011), and applied by Arnaud et al (2010) to render with empirically adjusted parameters the X-ray data out to R 500 for z 0.2. Actually, these analyses led to recognize an average profile along with a considerable variance.…”

Section: Introductionmentioning

confidence: 99%

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The Intracluster Plasma: A Universal Pressure Profile?

Lapi

Cavaliere

Fusco-Femiano

2012

ApJ

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The pressure profiles of the Intracluster Plasma in galaxy clusters show a wide variance when observed in X rays at low redshifts z 0.2. We find the profiles to follow two main patterns, featuring either a steep or a shallow shape throughout both core and outskirts. We trace these shapes back to a physical dichotomy of clusters into two classes, marked by either low entropy (LE) or high entropy (HE) throughout. From X-ray observations and Sunyaev-Zel'dovich stacked data at higher 0.2 z 0.4, we elicit evidence of an increasing abundance of HEs relative to LEs. We propose this to constitute a systematic trend toward high z; specifically, we predict the pressure profiles to converge into a truly universal HE-like template for z 0.5. We submit our physical templates and converging trend for further observational tests, in view of the current and upcoming measurements of individual, stacked, and integrated Sunyaev-Zel'dovich signals.

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Section: Introductionmentioning

confidence: 78%

Section: Introductionmentioning

confidence: 99%

The Intracluster Plasma: A Universal Pressure Profile?

Lapi

Cavaliere

Fusco-Femiano

2012

ApJ

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“…The lensing-tSZ cross-correlation power spectrum is the sum of two terms, C κy ℓ = C κy,1h ℓ + C κy,2h ℓ , where "1h" and "2h" refer to the 1-and 2-halo terms, respectively. The 1-halo term, the Poissonian contribution, is given by [8] C κy,1h [7]; blue dashed, the universal pressure (UP) profile [24]; green, the Komatsu-Seljak (KS) profile [23]; and purple, the isothermal β-model profile [26]. The data points in panel (b) show the correlation function specifically for tSZ data set "D".…”

Section: κ-Y Correlation Function In the Halo Modelmentioning

confidence: 99%

“…We consider three different gas models in this study: the Komatsu-Seljak (KS) profile [23]; the universal pressure (UP) profile [24]; and the isothermal β-model [25][26][27][28]. For the KS model, we use equations (D4)-(D13) in [29] to implement the pressure profile.…”

Section: Pressure Profile 41 Models For Gas Pressurementioning

confidence: 99%

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Probing the diffuse baryon distribution with the lensing-tSZ cross-correlation

Waerbeke

Hinshaw

et al. 2015

J. Cosmol. Astropart. Phys.

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Approximately half of the Universe's baryons are in a form that has been hard to detect directly. However, the missing component can be traced through the cross-correlation of the thermal Sunyaev-Zeldovich (tSZ) effect with weak gravitational lensing. We build a model for this correlation and use it to constrain the extended baryon component, employing data from the Canada France Hawaii Lensing Survey and the Planck satellite. The measured correlation function is consistent with an isothermal β-model for the halo gas pressure profile, and the 1-and 2-halo terms are both detected at the 4σ level. In addition, we measure the hydrostatic mass bias (1 − b) = 0.79 +0.07 −0.10 , which is consistent with numerical simulation results and the constraints from X-ray observations. The effective temperature of the gas is found to be in the range (7 × 10 5 -3 × 10 8 ) K, with approximately 50% of the baryons appearing to lie beyond the virial radius of the halos, consistent with current expectations for the warm-hot intergalactic medium.

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Evaluating the quality of red blood cell concentrates irradiated before or after cryopreservation

et al. 2019

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BACKGROUNDCryopreserved red blood cell concentrates (RCCs) are often required for patients with rare blood groups. Although transfusions from blood relatives are irradiated before transfusion, research has yet to make clear if this is necessary in cryopreserved RCCs. Given insufficient evidence to the contrary, irradiation of cryopreserved RCCs has been recommended, but the effect of irradiation timing is unknown. Therefore, this study was performed to assess the effect of RCC irradiation pre‐ and postcryopreservation on RCC quality.STUDY DESIGN AND METHODSNine whole blood units from healthy donors were processed into RCCs using the buffy coat method. ABO‐ and Rh‐matched units were pooled and split into three groups: precryopreservation irradiation (pre‐CIG), postcryopreservation irradiation (post‐CIG), and nonirradiated controls. Hemoglobin, hematocrit, white blood cell (WBC) count, extracellular potassium, mean cell volume, red blood cell (RBC) morphology, and RBC deformability were measured.RESULTSExtracellular potassium was greater in the irradiated conditions when compared to the nonirradiated controls and was greater in the post‐CIG group when compared to the pre‐CIG group (p < 0.05). WBC counts decreased after cryopreservation in all groups to values lower than the sensitivity of the assay. RBC deformability was greater in the post‐CIG group when compared to the pre‐CIG group and control group. No other significant differences were observed between groups.CONCLUSIONIrradiation of RCCs can be performed pre‐ or postcryopreservation with little effect on the RCC product, as both irradiated groups resulted in RCCs that were comparable to the nonirradiated cryopreserved RCCs.

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WBC reduction in cryopreserved RBC units

Abstract: RBC freezing alone will not reduce residual counts to recommended levels. However, initial removal of BC can provide an economical alternative to WBC filtration for cryopreserved units. Units that were not WBC reduced before freezing can be filtered after deglycerolization when needed.

Cited by 5 publications

References 26 publications

The Intracluster Plasma: A Universal Pressure Profile?

The Intracluster Plasma: A Universal Pressure Profile?

Probing the diffuse baryon distribution with the lensing-tSZ cross-correlation

Evaluating the quality of red blood cell concentrates irradiated before or after cryopreservation

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