Weak Magnetic Fields Enhance the Efficacy of Radiation Therapy

Abstract

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Static magnetic field assisted thawing improves cryopreservation of mouse whole ovaries

“…To date, SMF has been found to be effective in regulating the oxidation–reduction homeostasis of cells. In accordance with our observations, Wei et al found that MF therapy significantly reduced ROS accumulation and MDA production in the radiation‐injured model, while increasing the activity of antioxidant enzymes 53,54 . As mentioned in the literature review, the inhibitory effect of SMFs on Fe 2+ ‐induced ROS generation is limited to a field strength “window” of 2 to 4 mT 55 .…”

“…In accordance with our observations, Wei et al found that MF therapy significantly reduced ROS accumulation and MDA production in the radiation‐injured model, while increasing the activity of antioxidant enzymes. 53 , 54 As mentioned in the literature review, the inhibitory effect of SMFs on Fe 2+ ‐induced ROS generation is limited to a field strength “window” of 2 to 4 mT. 55 A strong relationship between ROS and the efficacy of cryopreservation has been reported.…”

Biophysics at the edge of life and death: Radical control of apoptotic mechanisms

“…The use of MFs to control cell activities has exciting clinical implications. For instance, non-invasive application of MFs in combination with radiotherapy was able to reduce ROS levels and enhance tumor cell specific apoptosis in vivo (Iwamoto et al, 2021). Similarly, ex vivo application of high-frequency electric fields to modulate ion flow has the potential to induce cancer cell death with reduced off-target effects (Fukushiro-Lopes et al, 2018;Berkelmann et al, 2019), as malignant cell types are often enriched in ion channels and have different membrane voltages than surrounding tissues (Ko et al, 2013;Williams et al, 2013).…”