The ORCID identification number(s) for the author(s) of this article can be found under https://doi.org/10.1002/adma.201902133.Wearable electronics have revolutionized the way physiological parameters are sensed, detected, and monitored. In recent years, advances in flexible and stretchable hybrid electronics have created emergent properties that enhance the compliance of devices to our skin. With their unobtrusive attributes, skin conformable sensors enable applications toward real-time disease diagnosis and continuous healthcare monitoring. Herein, critical perspectives of flexible hybrid electronics toward the future of digital health monitoring are provided, emphasizing its role in physiological sensing. In particular, the strategies within the sensor composition to render flexibility and stretchability while maintaining excellent sensing performance are considered. Next, novel approaches to the functionalization of the sensor for physical or biochemical stimuli are extensively covered. Subsequently, wearable sensors measuring physical parameters such as strain, pressure, temperature, as well as biological changes in metabolites and electrolytes are reported. Finally, their implications toward early disease detection and monitoring are discussed, concluding with a future perspective into the challenges and opportunities in emerging wearable sensor designs for the next few years.
Wearable SensorsRecent progress in flexible and stretchable electronic systems has ignited exciting applications in consumer electronics, human computer interactions, augmented reality devices, and electronic skins. [1][2][3] Among these, a significant interest lies in health monitoring, [4][5][6] where vital functions may be measured continuously. Continuous health monitoring is far more superior than conventional healthcare workflow as the conventional approach can only offer snapshots of the physiological condition Figure 3. Material substrates for flexible and stretchable electronics, highlighting the advantages of choices for each material type. a) Common polymeric materials by order of glass transition temperatures. Reproduced with permission. [29] Copyright 2015, Elsevier. b) Schematic representation of crosslinked elastomeric substrates possessing configuration entropy. Reproduced with permission. [22]