“…A total of 18 subjects with PD were recruited from different Parkinson associations located in Spain and Portugal who were in early stages (≤2) of the disease according to the Hoehn and Yahr (H&Y) scale [ 79 ] (age: 64.9 ± 7.6 [ 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 ] years; gender: 8 M/10 F; stage H&Y I/II/: 4/14). Patients had a good clinical response to levodopa and/or dopamine agonists and did not present dementia according to the diagnostic and statistical manual of mental disorders IV (DSM IV) criteria [ 78 ].…”