Weather, climate, and climate change all effect outdoor recreation and tourism, and will continue to cause a multitude of effects as the climate warms. We conduct a systematic literature review to better understand how weather, climate, and climate change affect outdoor recreation and nature-based tourism across the United States. We specifically explore how the effects differ by recreational activity, and how visitors and supply-side tourism operators perceive these effects and risks. The 82 papers reviewed show the complex ways in which weather, climate, and climate change may affect outdoor recreation, with common themes being an extended season to participate in warm-weather activities, a shorter season to participate in snow-dependent activities, and larger negative effects to activities that depend on somewhat consistent precipitation levels (e.g., snow-based recreation, water-based recreation, fishing). Nature-based tourists perceive a variety of climate change effects on tourism, and some recreationists have already changed their behavior as a result of climate change. Nature-based tourism suppliers are already noticing a wide variety of climate change effects, including shifts in seasonality of specific activities and visitation overall. Collectively, this review provides insights into our current understanding of climate change and outdoor recreation and opportunities for future research.