Weeds as Alternative Useful Medicinal Source: <i>Mimosa pudica</i> Linn. on Diabetes Mellitus and its Complications

Abstract

Diabetes mellitus is one of the major reasons for mortality worldwide and numerous scientific studies are going on to find plausible solutions to overcome and manage diabetes and its related infirmities. Traditional medicines use medicinal plants as anti-diabetic agents and despite being a disturbing weed to farming landMimosa pudicaLinn. has a high traditional usage for various purposes including anti-diabetic complications. The objective of this article is to accumulate and organise literatures based on traditional claims and correlate those with current findings on the use ofM. pudicain the management of diabetes mellitus.M. pudicais a creeping perennial shrub which is a common weed widely distributed in Southeast Asia specially in India, Bangladesh, Malaysia, China, Philippine etc. This plant has various species of whichM. pudicais a well recognised plant of medicinal origin which has been traditionally used as folk medicine in India, Bangladesh and Philippine, Chinese, herbal and siddha medicines. It has wound healing, anti-diabetic, anti-diarrhoeal, antimicrobial, anti-cancer, anti-infections, anti-worm, anti-proliferative, anti-snake venom, anti-depressant and anxiolytic etc. activities. The objective of this article is to provide up-to-date information on the traditional and scientific studies based on this plant on the frontier of diabetes mellitus. The methodology followed was to methodically collect, organise and chart the recent advances in the use ofM. pudicain diabetes and its related complications like vascular complications, diabetic wound, hyperlipidemia etc. Various scientific studies and traditional literatures clearly support the use ofM. pudicaas an anti-diabetic agent among other uses. So far, the anti-diabetic compounds have not been isolated from this plant and this can be a good scientific study for the future anti-diabetic implications.

Mimosa pudica L., a High‐Value Medicinal Plant as a Source of Bioactives for Pharmaceuticals

“…The extract and its fractions also showed free radical‐scavenging activity as determined by 1,1‐diphenyl‐2‐picrylhydrazyl‐hydrate (DPPH), total flavonoid content, and total phenolic content assays. The study revealed that M. pudica is a potential candidate to treat diabetes (Tunna and others , 2015).…”

Suku Fabaceae Di Kampus Universitas Islam Negeri Syarif Hidayatullah, Jakarta, Bagian 2: Tumbuhan Polong Berperawakan Terna

“…Pemanfaatan: Puteri malu ditanam sebagai tanaman penutup tanah di perkebunan kelapa dan pakan sapi (Soerjani et al, 1987). Selain itu, bagian akarnya juga dimanfaatkan sebagai obat diabetes oleh masyarakat di Bangladesh, India, Thailand, dan Filipina (Tunna et al, 2014).…”

Phytochemical Analysis and Antioxidant and Antidiabetic Activities of Extracts from Bergenia ciliata, Mimosa pudica, and Phyllanthus emblica

“…Some of the major chemical constituents of this species are chebulagic acid, chebulic acid, corilagin, phyllanemblinin A, gallic acid, ellagic acid, malic acid, mucic acid, (-)epicatechin, and mallonin [ 15 ]. M. pudica of the family Fabaceae commonly found in South Asian countries possesses antidiabetic, antibacterial, wound-healing, antivenom, and anticancer properties and is traditionally used for treatment of fever and dyspepsia [ 16 ]. Phytochemical analysis revealed the presence of flavonoids C-glycosides, sterols, terpenoids, tannins, fatty acids, p-coumaric acid, mimopudine, and mimosine in M. pudica [ 17 ].…”