Wege zu funktionalen Vesikelmembranen ohne Proteine

Fuhrhop, Jürgen‐Hinrich; Mathieu, Joachim

doi:10.1002/ange.19840960206

Cited by 76 publications

(33 citation statements)

References 57 publications

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“…A related morphology control is found for a mixture of 17 (12,4), and 21. Cosonication of multiwalled vesicles of 17 (12,4) and globular 21 gives single-walled vesicles.…”

Section: Morphology Of Bilayersmentioning

confidence: 81%

“…Figure 14 shows representative spectral variations which depend on the molecular structure. All the bi- (12,5). The observed A, , , variation needs to be explained in terms of the chromophore interaction (orientation and aggregation) in the aggregate.…”

Section: Molecular Orientation Within the Bilayermentioning

confidence: 96%

“…4). The major (12,15) gives single-compartment vesicles, whereas 5 (16, 15) produces paired bilayers (Fig. 5).…”

mentioning

confidence: 97%

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Synthetic Bilayer Membranes: Molecular Design, Self‐Organization, and Application

Kunitake¹

1992

Angew. Chem. Int. Ed. Engl.

683

408

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Lipid bilayers are a most central building block of the biological molecular organization. Their two-dimensional self-assembly is essential to the generation of biological shapes and sizes on the molecular level. The observation that a totally synthetic amphiphile in water is spontaneously assembled to a bilayer structure suggested that bilayer formation is a general physicochemical phenomenon that is not restricted to particular structures of biolipid molecules. Bilayer formation is now observed for a large variety of synthetic amphiphiles which contain one, two, three, or four alkyl tails. The flexible alkyl tail may be replaced by perfluoroalkyl chains. The supramolecular structures obtained therefrom can be related to the component's molecular structure in many cases. The structural variety and the ease of molecular design make the synthetic bilayer an attractive vehicle for organizing covalently bound functional units and guest molecules. In addition, stable monolayers on water, planar lipid membranes (BLM), and free-standing cast films are obtainable because of the self-assembling property of bilayer-forming compounds. These molecular organizations display common supramolecular features. The use of the cast film as a molecular template provides exciting potential for the production of novel two-dimensional materials.

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“…A related morphology control is found for a mixture of 17 (12,4), and 21. Cosonication of multiwalled vesicles of 17 (12,4) and globular 21 gives single-walled vesicles.…”

Section: Morphology Of Bilayersmentioning

confidence: 81%

Section: Molecular Orientation Within the Bilayermentioning

confidence: 96%

See 1 more Smart Citation

Synthetic Bilayer Membranes: Molecular Design, Self‐Organization, and Application

Kunitake¹

1992

Angew. Chem. Int. Ed. Engl.

683

408

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“…[1][2][3][4][5][6] Bolaamphiphiles are related to and often combined with "edge amphiphiles", where one flank of a hydrophobic core carries hydrophilic groups whereas the other edge is hydrophobic ( Figure 1). The terms "bolaform amphiphiles" or "bolaphiles" have also been used but do not make much sense.…”

Section: Introductionmentioning

confidence: 99%

Bolaamphiphiles

2004

Self Cite

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“…The interior of the lipid vesicles is an aqueous core, the chemical composition of which corresponds in a first approximation to the chemical composition of the aqueous solution in which the vesicles are prepared. Depending on the method of preparation, lipid vesicles can be multi-, oligo-or unilamellar, containing many, a few, or one bilayer shell(s), respectively; the diameter of the lipid vesicles may vary between about 20 nm and a few hundred micrometers [112][113][114][115][116][117].…”

Section: Vesiclesmentioning

confidence: 99%

Multifunctional Polymeric Nanostructures for Therapy and Diagnosis

Contreras-García¹,

Bucio²

2013

Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering

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By definition, nanomaterials are multifunctional due to the co-incorporation of both therapeutic and bioimaging agents. Among the therapeutic applications of the polymeric nanomaterials are found drug, protein or gene delivery, tissue engineering. Other advances in bioapplications include cell-labeling, cell membrane modeling, agent delivery and targeting. Additionally, imaging nanobiotechnology is applied to sensorization and diagnosis with biosensors and biomarkers for biodetection and bioimaging, respectively. In this chapter are described the different polymeric nanostructures applied to therapy and diagnosis such as polymeric-based core-shell colloid, proteins and peptides, drug conjugates and complexes with synthetic polymers, dendrimers, vesicles, micelles, carbon nanotubes, biopolymers, smart nano polymers, metal-polymer complexes, enzyme-responsive nanoparticles, and hybrid polymeric nanomaterials. The different types of polymers are fabricated using several approaches ranging from conventional chemical methods to more sophisticated processes such as surface modification using ionizing radiation to obtain layers free of pollutants without purification and isolation processes among other advantages.

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Wege zu funktionalen Vesikelmembranen ohne Proteine

Cited by 76 publications

References 57 publications

Synthetic Bilayer Membranes: Molecular Design, Self‐Organization, and Application

Synthetic Bilayer Membranes: Molecular Design, Self‐Organization, and Application

Bolaamphiphiles

Multifunctional Polymeric Nanostructures for Therapy and Diagnosis

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