Weight gain after 20 years of age is associated with prevalence of chronic kidney disease

Wakasugi, Minako; Narita, Ichiei; Iseki, Kunitoshi; Moriyama, Toshiki; Yamagata, Kunihiro; Tsuruya, Kazuhiko; Yoshida, Hiroyuki; Fujimoto, Shoichi; Asahi, Koichi; Kurahashi, Issei; Ohashi, Yasuo; Watanabe, Tsuyoshi

doi:10.1007/s10157-011-0565-3

Cited by 21 publications

(26 citation statements)

References 26 publications

(31 reference statements)

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“…An increase in weight by more than 1 kilogram / day suggests fluid retention (20) . A study showed a significant association between age and weight gain and identified an average age of 59 years (27) , which is consistent with this study.…”

Section: Discussionsupporting

confidence: 92%

Excess fluid volume: sociodemographic and clinical analysis in haemodialysis patients

et al. 2017

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Excess fluid volume: sociodemographic and clinical analysis in haemodialysis patients Fernandes MICD, et al. INTRODUCTIONChronic kidney disease (CKD) is progressive and irreversible kidney damage and is associated with decreased glomerular filtration rate. The filtration and renal regulation failure generates the accumulation of toxic substances in the body, triggering water, electrolyte, acid-base, endocrine and metabolic disorders (1) . Therefore, performing treatments that replace kidney functions is needed. Accordingly, haemodialysis (HD) plays a primary role. At of the end of the year 2012, 3,010,000 patients worldwide had end-stage renal disease. Of these, 70% underwent haemodialysis (2) . This therapy consists of blood filtration with the aid of a dialysis machine, through a dialyser, in which toxic substances and excess nitrogen liquid are excreted, and the function of the renal glomeruli and tubules is supported (1) . Despite the appropriate follow-up, this treatment does not completely replace renal function and causes the accumulation of excreta nitrogen, fluids and electrolytes, which are responsible for signalling the signs and symptoms in this clientele (3)(4) . Amongst the effects of renal impairment, liquid accumulation is a central problem in these individuals. This excess is the response to the water imbalance between entry and output of the liquids in the organisms, causing complications such as cardiovascular problems (5) . In this context, nursing care needs to directly address the actual customer's needs during haemodialysis. The identification of nursing diagnoses (ND), a step of the nursing process that helps to organise and direct care, translates human responses experienced by the customer in relation to their health condition (6) . The International ND from NANDA International (NAN-DA-I) "Excess fluid volume" is defined as increased retention of isotonic liquids (7) . It comprises 25 defining characteristics and three related factors (7) . Studies with patients submitted to haemodialysis have indicated the high prevalence of this nursing diagnosis (8)(9) , having a prevalence of 82% in patients undergoing haemodialysis. Moreover, the following characteristics were significantly associated with this diagnosis: agitation, pulmonary congestion, jugular distension, oedema, altered electrolytes, weight gain, feed intake greater than the debt and adventitious breath sounds (10) . Another study confirmed the above research and suggested that water retention is common in haemodialysis patients and is associated with worse outcomes, including various heart conditions such as tissue ischemia, arrhythmia and sudden cardiac death, in addition to acute pulmonary oedema and hypertension. Hypertension is an important risk factor for cardiovascular disease, which is commonly seen in populations with declining renal function (11)(12)(13) . Accordingly, the onset of renal replacement therapy partially decreases the symptoms of failing kidneys; however, high blood pressure levels persist in most patients...

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Section: Discussionsupporting

confidence: 92%

Excess fluid volume: sociodemographic and clinical analysis in haemodialysis patients

et al. 2017

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“…), as well as a risk factor for progression of chronic kidney disease (CKD) (Wakasugi et al . ). Diseases with multiple complications such as CKD are often managed with an integrated, multi‐disciplinary approach.…”

Section: Discussionmentioning

confidence: 97%

Nutrition Care for Renal Transplant Recipients: An Evaluation of Service Delivery and Outcomes

Orazio

Chapman

Isbel

et al. 2014

Journal of Renal Care

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Nutrition care provided did not meet guideline recommendations, highlighting difficulty in implementing evidence to practice. Significant weight gain was evident particularly in patients classified as 'healthy weight' at the time of transplant. Long-term, prospective studies are needed to determine the effectiveness of implementing nutrition care to attenuate weight gain and improve clinical outcomes.

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“…The SHC has been described elsewhere [14,15]. Briefly, the SHC is a new health-care strategy aimed at early diagnosis and intervention for metabolic syndrome, and was initiated by the Japanese government in 2008.…”

Section: Methodsmentioning

confidence: 99%

Association between Hypouricemia and Reduced Kidney Function: A Cross-Sectional Population-Based Study in Japan

Wakasugi¹,

Kazama²,

Narita³

et al. 2015

Am J Nephrol

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Background: Hypouricemia, conventionally defined as a serum uric acid level of ≤2 mg/dl, is considered a biochemical disorder with no clinical significance. However, individuals with renal hypouricemia have a high risk of urolithiasis and exercise-induced acute kidney injury, both of which are risk factors for reduced kidney function. Methods: To test the hypothesis that individuals with hypouricemia would be at a higher risk of reduced kidney function, we conducted a population-based cross-sectional study using data from the Specific Health Checkups and Guidance System in Japan. Logistic analysis was used to examine the relationship between hypouricemia and reduced kidney function, defined as estimated glomerular filtration rate <60 ml/min/1.73 m². Results: Among 90,710 men (mean age, 63.8 years) and 136,935 women (63.7 years), 193 (0.2%) and 540 (0.4%) were identified as having hypouricemia, respectively. The prevalence of hypouricemia decreased with age in women (p for trend <0.001), but not in men (p for trend = 0.24). Hypouricemia was associated with reduced kidney function in men (odds ratio, 1.83; 95% confidence interval, 1.23-2.74), but not in women (0.61; 0.43-0.86), relative to the reference category (i.e., serum uric acid levels of 4.1-5.0 mg/dl) after adjusting for age, drinking, smoking, diabetes, hypertension, hypercholesterolemia, obesity, and history of renal failure. Sensitivity analyses stratified by diabetic status yielded similar results. Conclusions: This study is the first to provide evidence that hypouricemia is associated with reduced kidney function in men. Further research will be needed to determine the long-term prognosis of individuals with hypouricemia.

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Weight gain after 20 years of age is associated with prevalence of chronic kidney disease

Abstract: Weight gain after 20 years of age is associated with CKD among Japanese, even those without metabolic syndrome.

Cited by 21 publications

References 26 publications

Excess fluid volume: sociodemographic and clinical analysis in haemodialysis patients

Excess fluid volume: sociodemographic and clinical analysis in haemodialysis patients

Nutrition Care for Renal Transplant Recipients: An Evaluation of Service Delivery and Outcomes

Association between Hypouricemia and Reduced Kidney Function: A Cross-Sectional Population-Based Study in Japan

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