Weight loss in cancer patients: a plea for a better awareness of the issue

Mariani, Luigi; Vullo, Salvatore Lo; Bozzetti, Federico

doi:10.1007/s00520-010-1075-7

Cited by 57 publications

(25 citation statements)

References 51 publications

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“…The central study database was held at the Fondazione IRCCS Istituto Nazionale Tumori of Milan where data collected on each patient were entered, checked for quality and completeness and elaborated. Details on the study protocol and preliminary results on the first 1,000 patients have been recently published [9], and database was previously utilized for two publications, one on weight loss and its association with digestive and systemic symptoms [10] and one on a definition and classification of cancer cachexia [11]. …”

Section: Methodsmentioning

confidence: 99%

The nutritional risk in oncology: a study of 1,453 cancer outpatients

Bozzetti

Mariani

Vullo

et al. 2012

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165

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PurposeThere is little information about the nutritional status of cancer outpatients because the practice of nutritional screening is rarely performed. This study aims to define the pattern of scores of nutritional risk in 1,453 outpatients and factors associated with a high nutrition risk score, to facilitate the identification of such patients by the oncologists.MethodsWe prospectively screened the nutritional status of cancer outpatients according to the NRS-2002 score which combines indicators of malnutrition and of severity of the disease (1–3 points, respectively). A score ≥3 indicates “nutritional risk”. The association of the nutritional scores with some patient/tumour/therapy-related variables was investigated through univariable and multivariable linear regression models.ResultsThirty-two percent of outpatients were at nutritional risk. Primary tumour site, Eastern Cooperative Oncology Group score and presence of anorexia or fatigue were significantly associated with the nutrition risk score. Depending on the combination of these variables, it was possible to estimate different probabilities of nutritional risk.ConclusionsThe frequency of a relevant nutritional risk was higher than expected considering the favourably selected population. The nutritional risk was associated with common clinical variables which are usually recorded in the charts and could easily alert the oncologist on the need of a further nutritional assessment or a nutritional support.

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Section: Methodsmentioning

confidence: 99%

The nutritional risk in oncology: a study of 1,453 cancer outpatients

Bozzetti

Mariani

Vullo

et al. 2012

Support Care Cancer

Self Cite

165

104

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show abstract

“…44 In an ongoing study on the nutritional status of cancer outpatients 45 we recently found that in 689 ≥ 65-year old subjects the mean weight loss was 9.5% (median value 8.2%) and percentage of patients with a weight loss ≥10% of their usual body weight was 42.5%. Moreover, the percentage of patients with a Nutritional Risk score ≥3 was 61.2%.…”

Section: Prevalence Of Malnutritionmentioning

confidence: 98%

Nutritional aspects of the cancer/aging interface

Bozzetti

2011

Journal of Geriatric Oncology

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“…12 Studies have demonstrated a high prevalence of malnutrition in elderly patients: >10% weight loss in 71%, BMI <20 in 44%, Mini Nutritional Assessment (MNA) <24 and low serum albumin in 66%. 13 Malnutrition is an important prognostic determinant of treatment outcome. Low BMI is associated with fewer oncologic therapies and poorer survival.…”

Section: Nutrition and Cancer Treatment Outcomementioning

confidence: 99%