“…The risk of psychological/ psychiatric illness remains unclear however, as investigations designed to examine psychological outcomes in long-term survivors of childhood cancer have produced inconsistent, and at times conflicting findings Kokkonen et al, 1997;Teta et al, 1986). Several studies suggest that childhood cancer survivors are at increased risk for maladaptive psychosocial sequalae (Koocher and O'Malley, 1981) including depression (Fritz et al, 1988;Mulhern et al, 1989), behavioral adjustment problems (Moore et al, 1987;Fritz et al, 1988;Mulhern et al, 1989;Madan-Swain and Brown, 1991), and anxiety (Zebrack and Chesler, 2002;Pendley et al, 1997;Neff and Beardslee, 1990), while others report that a significant portion of childhood cancer survivors have no higher prevalence of anxiety (Schmale et al, 1983), depression (Greenberg et al, 1989;Ross et al, 2003), overall mood disorder (Gray et al, 1992), or lowered self-concept (Anholt et al, 1993) when compared with population norms or matched controls. Moreover, a number of studies suggest that childhood cancer survivors are well-or better-adjusted compared to normative groups (Fritz et al, 1988;Barakat et al, 1997;Kazak, 1998;Cella and Tross, 1986;Kupst et al, 1995;Chesler and Zebrack, 1997).…”