“…Physics-based approaches can approximate the original reservoir behavior with lower-order equations to reduce the computational cost. However, they have been so far tested on synthetic, box-shaped models only (de Brito and Durlofsky, 2020a;de Brito and Durlofsky, 2020b) and can become unrepresentative in real fields with often complex structures. ML techniques are widely applied within the context of well control optimization (Ahmadi and Bahadori, 2015;Golzari et al, 2015;Chugh et al, 2016;Guo and Reynolds, 2018;Chen et al, 2020;Zhao et al, 2020) and are shown to provide a reasonably accurate, data-driven SM while considering the reservoir simulator as a black box.…”