The popularization of education on the administrative compulsion law in response to major epidemic situations in China refers to the educational activities carried out by an educational subject aimed at an educational object promoting understanding and mastery of knowledge of administrative compulsion. The goal is to improve the government’s legal ability to prevent and control behavior, enhance people’s awareness of the rule of law, and provide a strong legal basis for the rule of law in the context of major epidemics. Other aims are to cultivate citizens’ legal beliefs, restrain citizens’ conduct, and maintain a stable social order. However, problems arise in the subject, content, and mode of the educational activities. Therefore, we need to discuss compulsory education in the context of major epidemic situations, including the need for a favorable educational environment, the strengthening of information distribution, and the guidance of public opinion on administrative enforcement. We should also improve education subjects to enhance the legal quality of administrative organs, perfect the education content, encourage people to support administrative compulsion in epidemic situations, and deliver education in campus online classes.