REVIEWCT colonography has evolved rapidly over recent years into the best radiological method for investigating colonic neoplasia. Technological advances enable very fast CT scans (patients hold breath for less than 10 s per scan) with improved spatial resolution and lower radiation dose. User friendly reading software, incorporating computer aided diagnosis, enables radiologists to accurately review data in multiple anatomical planes, utilising both two-dimensional and 'endoluminal' three-dimensional displays. However, as demand for colonic investigation increases (particularly in an older, more frail population), alongside socio-political drives to reduce waiting times, the quality of interaction between endoscopy and radiology becomes of paramount importance. There are pros and cons for both CT colonography and endoscopy and their relative benefits can be fully exploited by closely aligned gastroenterology and radiology teams, potentially improving diagnostic efficiency and patient experience. This review will update gastroenterologists on current CT colonography techniques and will emphasise the need for strong partnership between endoscopy and radiology colon imaging services.