Wet-spinnability and crosslinked Fiber properties of alginate/hydroxyethyl cellulose with varied proportion for potential use in tendon tissue engineering

Hojabri, Mahsa; Tayebi, Tahereh; Kasravi, Mohammadreza; Aghdaee, Amirhossein; Ahmadi, Armin; Mazloomnejad, Radman; Tarasi, Roghayeh; Shaabani, Alireza; Bahrami, Soheyl; Niknejad, Hassan

doi:10.1016/j.ijbiomac.2023.124492

Cited by 22 publications

(4 citation statements)

References 80 publications

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“…However, CS and AL possess cytocompatibility; their antibacterial characteristics are insufficient to prevent wound infections. , Therefore, using another component of wound-dressing materials is crucial to reducing the therapy period . Antibacterial components could be added to scaffolds as carriers to control the release of active components such as antibacterial drugs to prevent infections. , Tyrosol is a phenylethanoid, a derivative of phenethyl alcohol, which is found in many natural sources as a natural phenolic antioxidant .…”

Section: Introductionmentioning

confidence: 99%

RETRACTED: 3D Printing of Alginate/Chitosan-Based Scaffold Empowered by Tyrosol-Loaded Niosome for Wound Healing Applications: In Vitro and In Vivo Performances

Beram,

Ali,

Mesbahian

et al. 2024

ACS Appl. Bio Mater.

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spinning and 3D printing techniques for wound healing applications. The niosomes, measuring 185.40 ± 6.40 nm with a polydispersity index of 0.168 ± 0.012, encapsulated tyrosol with an efficiency of 77.54 ± 1.25%. The scaffold's microsized porous structure (600−900 μm) enhances water absorption, promoting cell adhesion, migration, and proliferation. Mechanical property assessments revealed the scaffold's enhanced resilience, with niosomes increasing the compressive strength, modulus, and strain to failure, indicative of its suitability for wound healing. Controlled tyrosol release was demonstrated in vitro, essential for therapeutic efficacy. The scaffold exhibited significant antibacterial activity against Pseudomonas aeruginosa and Staphylococcus aureus, with substantial biofilm inhibition and downregulation of bacterial genes (ndvb and icab). A wound healing assay highlighted a notable increase in MMP-2 and MMP-9 mRNA expression and the wound closure area (69.35 ± 2.21%

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Section: Introductionmentioning

confidence: 99%

RETRACTED: 3D Printing of Alginate/Chitosan-Based Scaffold Empowered by Tyrosol-Loaded Niosome for Wound Healing Applications: In Vitro and In Vivo Performances

Beram,

Ali,

Mesbahian

et al. 2024

ACS Appl. Bio Mater.

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“…These innovations inspired the development of fiber-like hydrogel encapsulation for pancreatic islet cells. Besides, the double crosslinked hydrogels based on sodium alginate by employing hydrogels, such as PEGDA [ 81 ], cellulose nanocrystals [ 82 ], and hydroxyethyl cellulose [ 83 ], have also been generated to improve the mechanical toughness of the hydrogel fibers while maintaining good biocompatibility.…”

Section: Strategies For Encapsulating Islet Cellsmentioning

confidence: 99%

Hydrogel-Encapsulated Pancreatic Islet Cells as a Promising Strategy for Diabetic Cell Therapy

Huan,

Li,

Luo

et al. 2024

Research

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Islet transplantation has now become a promising treatment for insulin-deficient diabetes mellitus. Compared to traditional diabetes treatments, cell therapy can restore endogenous insulin supplementation, but its large-scale clinical application is impeded by donor shortages, immune rejection, and unsuitable transplantation sites. To overcome these challenges, an increasing number of studies have attempted to transplant hydrogel-encapsulated islet cells to treat diabetes. This review mainly focuses on the strategy of hydrogel-encapsulated pancreatic islet cells for diabetic cell therapy, including different cell sources encapsulated in hydrogels, encapsulation methods, hydrogel types, and a series of accessorial manners to improve transplantation outcomes. In addition, the formation and application challenges as well as prospects are also presented.

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“…The use of paper has shown an explosive growth trend in the past decades, which has not only caused the decrease of trees but also caused great damage to the atmospheric environment. , Cellulose, as the main component in paper, has the characteristics of renewability and biodegradability and is an environmentally friendly material with a wide range of uses. , Nowadays, cellulose has become an important part of many high-tech fields (such as the chemical industry, materials, medical treatment, etc. ). − At the same time, cellulose is also one of the common polysaccharides that are often used to discuss its internal structure and bonding in the teaching of polymer chemistry . However, the current experiments carried out in the laboratory ignore the combination of waste paper and cellulose for tandem education .…”

Section: Introductionmentioning

confidence: 99%

From Waste Paper to Cellulose: Building Environmental Awareness by Chemical Technology from Pragmatistic Pedagogy

Chen,

Zhang,

Yue

et al. 2024

J. Chem. Educ.

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With the increase of waste paper, environmental pollution and atmospheric impact have become global problems. The cellulose contained in waste paper has the advantages of being renewable and biodegradable and can be applied to many fields to achieve sustainable development. At present, thermal management materials, as a new type of material, have been proved to have potential advantages in environmental protection and resource conservation. Thermal management materials based on cellulose can not only recycle waste paper but also expand thermal management materials to different fields. In this experiment, the senior undergraduates cultivated the awareness of green environmental protection by extracting cellulose from waste paper and then completed the construction and performance exploration of thermal management materials under the guidance of teachers. The simple representations involved in this experiment can enable undergraduates to connect with the knowledge of analytical chemistry, polymer chemistry, and other subjects learned in the classroom and enable students to combine theory with practice. In addition, the positive feedback received from the students indicates that the experiment effectively serves as a compelling platform for teaching polymer chemistry and analytical chemistry and closely links the latest scientific research results with the laboratory experiments of undergraduate students. This work not only cultivates students' awareness of environmental protection but also stimulates their interest in advanced materials, which can be used as a springboard for them to become material scientists in the future.

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Wet-spinnability and crosslinked Fiber properties of alginate/hydroxyethyl cellulose with varied proportion for potential use in tendon tissue engineering

Cited by 22 publications

References 80 publications

RETRACTED: 3D Printing of Alginate/Chitosan-Based Scaffold Empowered by Tyrosol-Loaded Niosome for Wound Healing Applications: In Vitro and In Vivo Performances

RETRACTED: 3D Printing of Alginate/Chitosan-Based Scaffold Empowered by Tyrosol-Loaded Niosome for Wound Healing Applications: In Vitro and In Vivo Performances

Hydrogel-Encapsulated Pancreatic Islet Cells as a Promising Strategy for Diabetic Cell Therapy

From Waste Paper to Cellulose: Building Environmental Awareness by Chemical Technology from Pragmatistic Pedagogy

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