Wettability of porous polydimethylsiloxane surface: morphology study

Khorasani, Mohammad Taghi; Mirzadeh, Hamid; Kermani, Z. Peyvand

doi:10.1016/j.apsusc.2004.08.035

Cited by 257 publications

(135 citation statements)

References 20 publications

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“…Electrospinning changes porosity and roughness of the membrane which is a valid parameter in wettability [38]. Figure 4 displays the contact angles in two different conditions.…”

Section: Surface Modificationmentioning

confidence: 99%

Plasma based surface modification of Poly (dimethylsiloxane) electrospun membrane proper for Organ On a Chip applications

et al. 2018

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Constructing of the scaffolds for cell culture applications has long been of interest for engineering researchers and biologist. In this study, a novel process is utilized for construction of suitable membrane with a high mechanical strength and appropriate surface behavior. Poly (dimethylsiloxane) (PDMS) is electrospun into fine fibers using poly (methyl methacrylate) (PMMA) as the carrier polymer in different weight ratios.Since the surface behavior of all PDMS substrates is moderately hydrophobic (120 < contact angle (CA) < 150), the electrospun membranes with higher PDMS ratios show slightly higher hydrophilicity. Direct plasma treatment is utilized to change the interfacial wettability of the membrane. Applying plasma changes the surface energy and renders the PDMS/PMMA substrates superhydrophilic (CA<5). In the following, the mechanical properties of the membrane are evaluated by the tensile test, and the results confirm the suitable mechanical strength of electrospun PDMS for cell culturing objectives (yield stress of more than 10 kPa). Also, changing the PDMS ratio doesn't significantly affect the total stiffness of the membrane. Thus, applying the proposed fabrication protocol provides a proper platform for cell viability and proliferation which have been proven by the results of MTT assay.2

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“…Electrospinning changes porosity and roughness of the membrane which is a valid parameter in wettability [38]. Figure 4 displays the contact angles in two different conditions.…”

Section: Surface Modificationmentioning

confidence: 99%

Plasma based surface modification of Poly (dimethylsiloxane) electrospun membrane proper for Organ On a Chip applications

et al. 2018

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“…This was repeatedly observed for the first 3 PDMS casts from the silane coated epoxy masters despite the application of PDMS sterilization techniques. Due to the inherent porous structure of PDMS polymer, 26 organic elements such as silane can be absorbed and leached into culture media causing toxicity when culturing cells. 27 As an alternative viable option, we coated epoxy masters with the biocompatible surface metal, gold, using chromium as an adhesion promoter.…”

Section: Biocompatibilitymentioning

confidence: 99%

Cloning SU8 silicon masters using epoxy resins to increase feature replicability and production for cell culture devices

2015

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In recent years, there has been a dramatic increase in the use of poly(dimethylsiloxane) (PDMS) devices for cell-based studies. Commonly, the negative tone photoresist, SU8, is used to pattern features onto silicon wafers to create masters (SU8-Si) for PDMS replica molding. However, the complexity in the fabrication process, low feature reproducibility (master-to-master variability), silane toxicity, and short life span of these masters have been deterrents for using SU8-Si masters for the production of cell culture based PDMS microfluidic devices. While other techniques have demonstrated the ability to generate multiple devices from a single master, they often do not match the high feature resolution ($0.1 lm) and low surface roughness that soft lithography masters offer. In this work, we developed a method to fabricate epoxy-based masters that allows for the replication of features with high fidelity directly from SU8-Si masters via their PDMS replicas. By this method, we show that we could obtain many epoxy based masters with equivalent features to a single SU8-Si master with a low feature variance of 1.54%. Favorable feature transfer resolutions were also obtained by using an appropriate Tg epoxy based system to ensure minimal shrinkage of features ranging in size from $100 lm to <10 lm in height. We further show that surface coating epoxy masters with Cr/Au lead to effective demolding and yield PDMS chambers that are suitable for long-term culturing of sensitive primary hippocampal neurons. Finally, we incorporated pillars within the Au-epoxy masters to eliminate the process of punching media reservoirs and thereby reducing substantial artefacts and wastage. V C 2015 AIP Publishing LLC. [http://dx

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“…Hydrophobic materials are commonly applied onto textured surfaces to promote hydrophobicity. Teflon [116,117], PFOS (perfluoro-octane sulfonates) [118], PDMS (polydimethylsiloxane) [119], and CNTs (carbon nanotubes) [120,121,122] are representative examples. CVD (chemical vapor deposition), PVD (plasma vapor deposition), and electrochemical deposition techniques are commonly used to coat these materials.…”

Section: Dwc On Textured Surfacementioning

confidence: 99%

Nanotechnology for Advanced Nuclear Thermal-Hydraulics and Safety: Boiling and Condensation

Bang¹,

Jeong²

2011

Nuclear Engineering and Technology

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Wettability of porous polydimethylsiloxane surface: morphology study

Cited by 257 publications

References 20 publications

Plasma based surface modification of Poly (dimethylsiloxane) electrospun membrane proper for Organ On a Chip applications

Plasma based surface modification of Poly (dimethylsiloxane) electrospun membrane proper for Organ On a Chip applications

Cloning SU8 silicon masters using epoxy resins to increase feature replicability and production for cell culture devices

Nanotechnology for Advanced Nuclear Thermal-Hydraulics and Safety: Boiling and Condensation

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