Soccer participation among children and adolescents is low in China. To achieve a coordinated development of soccer in all regions and to promote the physical health of children and adolescents, this study aims to identify the influencing factors regarding the participation of children and adolescents in soccer programs through a cross-sectional analysis of the “soccer population” of children and adolescents. A total of 38,258 children and adolescents aged 7–18 years were included in this study. In addition, the analysis was conducted by dividing the regions where the children and adolescents live into three parts according to socioeconomic status, and by incorporating five dimensions, including environment, family, school, community, and individual levels to find the influencing factors of children and adolescents’ participation in soccer. Chi-square test, Pearson’s correlation, and one-way logistic regression analyses were used. The results showed that the area (r = 0.487) and the average annual precipitation (r = −0.367) were associated with the participation of children and adolescents in soccer programs. Moreover, the percentage of children and adolescents who participated in soccer programs (24.5%) was higher than those who liked soccer or were proficient in it (14.4%). Meanwhile, parental encouragement and support (OR = 0.627; 95% CI, 1.102–3.179), as well as the accessibility (OR = 0.558; 95% CI, 1.418–2.155), availability (OR = 1.419; 95% CI, 1.179–1.707), and safety of sports facilities (OR = 0.316; 95% CI, 0.614–0.865), influence children and adolescents’ participation in soccer programs.