2022
DOI: 10.1002/etc.5520
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What Approaches Should be Used to Prioritize Pharmaceuticals and Personal Care Products for Research on Environmental and Human Health Exposure and Effects?

Abstract: Pharmaceuticals and personal care products (PPCPs) are released from multiple anthropogenic sources and thus have a ubiquitous presence in the environment. The environmental exposure and potential effects of PPCPs on biota and humans has aroused concern within the scientific community and the public. Risk assessments are commonly conducted to evaluate the likelihood of chemicals including PPCPs that pose health threats to organisms inhabiting various environmental compartments and humans. Because thousands of … Show more

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Cited by 8 publications
(6 citation statements)
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“…Taken together, the papers in the special issue show that significant progress has been made since 2012 in developing our understanding of the inputs, occurrence, fate, effects, and risks of PPCPs in the environment and of advancing approaches to characterize and manage PPCP risks. In terms of prioritization, a range of exposure‐, hazard‐, and risk‐based approaches have been developed and applied to identify PPCPs of most concern in the environment (Mo et al, 2024). These approaches have now been applied to a wide range of geographies, giving us an insight into which PPCPs are of most concern in different regions of the world (Mo et al, 2024).…”
Section: Progress Over the Last Decadementioning
confidence: 99%
“…Taken together, the papers in the special issue show that significant progress has been made since 2012 in developing our understanding of the inputs, occurrence, fate, effects, and risks of PPCPs in the environment and of advancing approaches to characterize and manage PPCP risks. In terms of prioritization, a range of exposure‐, hazard‐, and risk‐based approaches have been developed and applied to identify PPCPs of most concern in the environment (Mo et al, 2024). These approaches have now been applied to a wide range of geographies, giving us an insight into which PPCPs are of most concern in different regions of the world (Mo et al, 2024).…”
Section: Progress Over the Last Decadementioning
confidence: 99%
“…might benefit from it, as they might have a better chance of preying on algae with relatively high nutrition values. However, a potential health risk is that these algae might contain certain levels of antibiotics and their residues, causing dietary exposures to these grazers [6]. Notably, it has been reported that erythromycin induced hormesis in toxin-producing cyanobacteria (e.g., M. aeruginosa and M. flos-aquae), which seriously threaten environmental health [13,19,23].…”
Section: Environmental Implicationsmentioning
confidence: 99%
“…Acceleration within these efforts, along with developments in precision medicine and precision environmental health science, has provided a foundation from which precision ecotoxicology can move forward. However, much more basic and translational work is needed across scales of biological organization and environmental gradients for PPCPs within the context of other stressors (Mo et al, 2024;Sumpter et al, 2024). As with other basic science advances within the ecotoxicology discipline, translation to the practice of risk assessment will be crucial to advance environmental management (Oldenkamp et al, 2024).…”
Section: Future Perspectivesmentioning
confidence: 99%
“…Over the past decade, advances in omics, AOPs, and population and bioenergetic modeling efforts in ecotoxicology have afforded unprecedented opportunities to begin to answer, “What can be learned about the evolutionary conservation of PPCP targets across species and life stages in the context of potential adverse outcomes and effects?” Acceleration within these efforts, along with developments in precision medicine and precision environmental health science, has provided a foundation from which precision ecotoxicology can move forward. However, much more basic and translational work is needed across scales of biological organization and environmental gradients for PPCPs within the context of other stressors (Mo et al, 2024; Sumpter et al, 2024). As with other basic science advances within the ecotoxicology discipline, translation to the practice of risk assessment will be crucial to advance environmental management (Oldenkamp et al, 2024).…”
Section: Future Perspectivesmentioning
confidence: 99%