What are the effects of rhinitis on patients with asthma?

Licari, Amelia; Manti, Sara; Ciprandi, Giorgio

doi:10.1080/17476348.2019.1604227

Cited by 12 publications

(7 citation statements)

References 20 publications

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“…Allergic rhinitis (AR) is a common disorder that afflicts 400 million people worldwide and it represents a global concern as its prevalence has increased over the years ( 1 ). AR usually comorbids with other diseases such as asthma ( 2 ), leading to impaired quality of life, school or work performance, and significant financial impact. AR is shown to be caused by aberrantly high Th2 cytokines, and recent findings on the cause of AR are directed toward impairment of the nasal epithelial barrier integrity ( 3 – 8 ).…”

Section: Introductionmentioning

confidence: 99%

Allergic Rhinitis: A Clinical and Pathophysiological Overview

et al. 2022

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Allergic rhinitis (AR) represents a global health concern where it affects approximately 400 million people worldwide. The prevalence of AR has increased over the years along with increased urbanization and environmental pollutants thought to be some of the leading causes of the disease. Understanding the pathophysiology of AR is crucial in the development of novel therapies to treat this incurable disease that often comorbids with other airway diseases. Hence in this mini review, we summarize the well-established yet vital aspects of AR. These include the epidemiology, clinical and laboratory diagnostic criteria, AR in pediatrics, pathophysiology of AR, Th2 responses in the disease, as well as pharmacological and immunomodulating therapies for AR patients.

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Section: Introductionmentioning

confidence: 99%

Allergic Rhinitis: A Clinical and Pathophysiological Overview

et al. 2022

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“…Diferentes fenotipos de rinitis, alérgica, alérgica local, no alérgica y rinosinusitis con y sin pólipos, pueden tener un impacto negativo sobre otras patologías de vía aérea inferior como asma, bronquiectasias, enfermedad fibroquística y enfermedad pulmonar obstructiva crónica (EPOC) (1,2) . De ellos, el modelo más estudiado es el de la interconexión existente entre rinitis, en sus fenotipos alérgico y no alérgico y asma (3)(4)(5)(6)(7)(8) . Esta establecido definitivamente que rinitis y asma frecuentemente coexisten de un modo más frecuente que lo esperado por azar.…”

Section: Problemaunclassified

“…Esto tiene directas implicancias diagnósticas y terapéuticas que no deben soslayarse en el abordaje médico. La mayoría de las comprobaciones clínicas y los estudios fármaco-económicos establecen una repercusión negativa de la rinitis sobre el control del asma tanto en niños como adultos (4,7,12) . El efecto inverso, del asma sobre la rinitis, ha sido menos estudiado.…”

Section: Problemaunclassified

“…Estos hallazgos sugieren que una disminución en la inflamación y la mejoría de la función nasal podría provocar una disminución de la reactividad e inflamación en la vía aérea intratorácica y una mejoría sintomática del asma o de los déficits de función pulmonar existentes. Algunos autores, postulan que una mejoría de la función nasal consecuente a uso de EIN, permitiría una recuperación de la capacidad de filtrado y acondicionado del aire inspirado con repercusión favorable para la vía aérea inferior (5,7) . La posibilidad de un efecto sistémico de los EIN aplicados en nariz, aunque factible, no estaría exento de efectos adversos, por lo que es una hipótesis difícilmente aceptable.…”

Section: Rinitis Con Esteroides Intranasales Sobre E L Asmaunclassified

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La necesidad de un abordaje integrado de la rinitis y el asma

Saranz

Lozano

et al. 2023

Rev Fac Cien Med Univ Nac Cordoba

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Introducción: Numerosas evidencias sustentan el concepto de unidad de la vía aérea y sus consiguientes implicancias fisiopatológicas, clínicas y terapéuticas. La existencia de rinitis puede generar una mayor dificultad para el control del asma y mayores costos sanitarios directos e indirectos, lo que no es suficientemente reconocido por la mayoría de los médicos que las tratan, generalmente, como entidades separadas. Objetivo: Examinar evidencias testigos de la relación entre rinitis y asma que favorezcan el abordaje integrado de ambas patologías. Métodos: Se realizó una búsqueda bibliográfica en bases de datos PubMed (Medline), EBSCO, Scielo, Google Scholar utilizando términos MeSH y DeCS vinculados a la relación clínica y terapéutica entre rinitis y asma. Resultados: Finalmente se incluyeron 46 referencias bibliográficas que describen el impacto de la rinitis sobre la calidad de vida de pacientes con asma y su correlato terapéutico. Conclusiones: El tratamiento de ambas enfermedades fundamentado en un modelo integrado es imperativo. El reconocimiento endo-fenotípico conjunto y la decisión terapéutica consecuente permite en control simultáneo del asma y la rinitis y una disminución de su morbilidad. La adopción de medidas terapéuticas complementarias basadas en el concepto “una vía aérea, una única enfermedad” se corresponde con las buenas prácticas clínicas necesarias para lograr el mejor resultado terapéutico.

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“…Allergic rhinitis (AR) has become a significant public health issue worldwide, as its prevalence has been on the rise in recent decades ( 1 ). It is common for individuals with comorbidities such as asthma to also experience AR, which can result in reduced quality of life, academic or job-related performance, and significant financial strain ( 2 ). AR affects 10–20% of the population worldwide, particularly as much as 40% of the population in industrialized countries; and 45% of the population in Asia ( 3 , 4 ).…”

Section: Introductionmentioning

confidence: 99%

Incidence of grass and weed sensitization in Bangkok, Thailand: a clinical study

Aud-in,

Juprasong,

Pinkaew

et al. 2024

Front. Public Health

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BackgroundAllergic rhinitis (AR) is a prevalent public health concern globally, significantly impacting quality of life. In Thailand, the prevalence of AR is rising, with grass and weed pollen identified as primary outdoor triggers.ObjectivesThis study aimed to (1) assess patterns of pollen sensitization in Thai AR patients and (2) investigate correlations between demographics/clinical data and SPT results.MethodsA total of 121 individuals aged ≥18 years with clinically diagnosed AR were recruited. Skin prick testing (SPT) was performed using a panel of commonly encountered tropical grass and weed pollen extracts. SPT wheal sizes and clinical symptom scores were recorded. Correlations between SPT outcomes and symptom scores were analyzed.ResultsAmong the participants, 104 (85.95%) exhibited positive SPT reactions to at least one pollen type. Nutsedge (76/121), para grass (57/121), and Bermuda grass (48/121) were the most frequently identified allergens. Hurricane grass elicited the strongest reaction, evidenced by the highest average wheal size (6.2 mm). Poly-sensitization was observed in 77 (63.6%) of the SPT-positive individuals, with most cases involving two different pollen extracts (35/77). Notably, AR severity positively correlated with both average wheal size and the number of positive SPT tests.ConclusionThis study highlights nutsedge, para grass, and Bermuda grass as major allergenic pollen sources for Thai AR patients. Including nutsedge, hurricane grass, and careless weed in clinical SPT panels is recommended for improved diagnostic accuracy. Additionally, the positive correlation between AR severity and pollen reaction strength emphasizes the importance of implementing patient education and avoidance strategies.

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What are the effects of rhinitis on patients with asthma?

Cited by 12 publications

References 20 publications

Allergic Rhinitis: A Clinical and Pathophysiological Overview

Allergic Rhinitis: A Clinical and Pathophysiological Overview

La necesidad de un abordaje integrado de la rinitis y el asma

Incidence of grass and weed sensitization in Bangkok, Thailand: a clinical study

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